Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study

Table 4 Genotype and allele frequencies between early-onset or late-onset PE and control

Group	N	rs2228000					rs2228001
Group	N	CC	CT	TT	C	T	TT	GT	GG	T	G
Early-onset PE	486	112	226	148	450	522	219	211	56	649	323
Control	1276	232	541	503	1005	1547	545	560	171	1650	902
χ2		13.286			9.098		1.43			1.388
P-value		0.001			0.003		0.489			0.239
OR						0.909				1.033
95%CI				0.852-0.969					0.98-1.089
Late-onset PE	472	77	284	111	438	506	189	233	50	611	333
Control	1276	232	541	503	1005	1547	545	560	171	1650	902
χ2		48.54			14		5.012			0.001
P-value		< 0.001			< 0.001		0.082			0.97
OR						0.884				1.001
95%CI				0.827 ~ 0.926					0.947-1.058

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