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Table 6 Comparison of embryological outcomes between the control and FCP subgroups in couples undergoing ICSI

From: Diverse impacts of female chromosomal polymorphisms on assisted reproduction outcomes: a retrospective cohort study

 

EMM ± SEM

Coefficient (95% CI)

P value

Oocytes retrieved

Control

12.8 ± 0.1

Ref.

Ref.

qh+

12.7 ± 0.7

−0.15(−1.52 ~ 1.21)

0.828

pstk+

13.2 ± 0.8

0.38(− 1.15 ~ 1.90)

0.629

inv(9)

14.0 ± 1.1

1.11(−1.11 ~ 3.33)

0.325

multiple

13.0 ± 1.4

0.16(−2.49 ~ 2.81)

0.906

others

13.9 ± 1.5

1.07(−1.95 ~ 4.10)

0.487

Metaphase II (M II) oocytes

Control

9.9 ± 0.1

Ref.

Ref.

qh+

9.5 ± 0.6

−0.43(−1.53 ~ 0.66)

0.436

pstk+

10.1 ± 0.6

0.19(−1.04 ~ 1.41)

0.767

inv(9)

10.7 ± 0.9

0.79(−0.99 ~ 2.56)

0.385

multiple

9.4 ± 1.1

−0.53(−2.66 ~ 1.59)

0.622

others

10.0 ± 1.2

0.02(−2.40 ~ 2.44)

0.986

Oocyte maturation rate (%)

Control

78.8 ± 0.3

Ref.

Ref.

qh+

75.8 ± 1.6

−0.03(−0.06 ~ 0.00)

0.073

pstk+

78.2 ± 1.9

−0.01(− 0.04 ~ 0.03)

0.740

inv(9)

76.5 ± 2.7

−0.02(− 0.08 ~ 0.03)

0.397

multiple

74.6 ± 3.2

−0.04(− 0.11 ~ 0.02)

0.197

others

69.0 ± 3.7

−0.10(− 0.17 ~ − 0.03)

0.008

Normal fertilization rate (%)

Control

63.8 ± 0.4

Ref.

Ref.

qh+

58.8 ± 2.3

−0.05(−0.10 ~ 0.00)

0.032

pstk+

62.9 ± 2.6

−0.01(− 0.06 ~ 0.04)

0.722

inv(9)

67.2 ± 3.8

0.03(−0.04 ~ 0.11)

0.367

multiple

56.3 ± 4.5

−0.08(− 0.17 ~ 0.01)

0.099

others

57.8 ± 5.2

−0.06(− 0.16 ~ 0.04)

0.253

Cleavage rate (%)

Control

98.5 ± 0.1

Ref.

Ref.

qh+

97.8 ± 0.7

−0.01(−0.02 ~ 0.01)

0.341

pstk+

98.3 ± 0.8

0.00(−0.02 ~ 0.01)

0.791

inv(9)

99.1 ± 1.2

0.01(−0.02 ~ 0.03)

0.631

multiple

99.6 ± 1.4

0.01(−0.02 ~ 0.04)

0.439

others

100.0 ± 1.7

0.02(−0.02 ~ 0.05)

0.359

Transplantable embryo rate (%)

Control

58.5 ± 0.6

Ref.

Ref.

qh+

58.2 ± 3.0

0.00(−0.06 ~ 0.06)

0.914

pstk+

54.5 ± 3.4

−0.04(− 0.11 ~ 0.03)

0.248

inv(9)

65.3 ± 5.0

0.07(−0.03 ~ 0.17)

0.174

multiple

53.0 ± 5.9

−0.06(− 0.17 ~ 0.06)

0.344

others

71.2 ± 7.0

0.13(−0.01 ~ 0.26)

0.071

  1. FCP female chromosomal polymorphism, EMM estimated marginal mean, SEM standard error of the means, CI confidence interval, Ref reference
  2. The EMMs, coefficients with their corresponding 95% CIs, and P values were calculated using generalized linear regression models
  3. P values less than 0.050 were shown in bold