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Table 4 Comparison of embryological outcomes between the control and FCP subgroups in couples undergoing IVF

From: Diverse impacts of female chromosomal polymorphisms on assisted reproduction outcomes: a retrospective cohort study

 

EMM ± SEM

Coefficient (95% CI)

Adjusted P value

Oocytes retrieved

Control

11.7 ± 0.1

Ref.

Ref.

qh+

10.9 ± 0.5

− 0.76(−1.73 ~ 0.22)

0.128

pstk+

12.2 ± 0.5

0.48(−0.54 ~ 1.50)

0.357

inv(9)

12.2 ± 0.9

0.49(−1.22 ~ 2.19)

0.578

multiple

12.6 ± 1.0

0.90(−0.99 ~ 2.79)

0.352

others

10.8 ± 1.0

−0.88(−2.78 ~ 1.03)

0.368

Normal fertilization rate (%)

Control

59.2 ± 0.3

Ref.

Ref.

qh+

63.0 ± 1.6

0.04(0.01 ~ 0.07)

0.022

pstk+

59.6 ± 1.7

0.00(−0.03 ~ 0.04)

0.819

inv(9)

64.2 ± 2.9

0.05(−0.01 ~ 0.11)

0.085

multiple

56.4 ± 3.2

−0.03(− 0.09 ~ 0.04)

0.386

others

57.7 ± 3.2

−0.02(− 0.08 ~ 0.05)

0.639

Cleavage rate (%)

Control

97.6 ± 0.1

Ref.

Ref.

qh+

98.4 ± 0.6

0.01(0.00 ~ 0.02)

0.202

pstk+

96.9 ± 0.6

−0.01(−0.02 ~ 0.01)

0.259

inv(9)

96.6 ± 1.1

−0.01(− 0.03 ~ 0.01)

0.358

multiple

97.4 ± 1.2

0.00(−0.03 ~ 0.02)

0.863

others

95.6 ± 1.2

−0.02(− 0.04 ~ 0.00)

0.099

Transplantable embryo rate (%)

Control

52.4 ± 0.4

Ref.

Ref.

qh+

52.2 ± 1.9

0.00(−0.04 ~ 0.04)

0.922

pstk+

50.9 ± 2.1

−0.02(− 0.06 ~ 0.03)

0.470

inv(9)

54.7 ± 3.4

0.02(−0.05 ~ 0.09)

0.503

multiple

47.2 ± 3.8

−0.05(− 0.13 ~ 0.02)

0.175

others

53.8 ± 3.8

0.01(−0.06 ~ 0.09)

0.713

  1. FCP female chromosomal polymorphism, EMM estimated marginal mean, SEM standard error of the means, CI confidence interval, Ref reference
  2. The EMMs, coefficients with their corresponding 95% CIs, and adjusted P values were calculated using generalized linear regression models. The embryological outcomes, except for the oocytes retrieved, were adjusted for the paternal factor
  3. P values less than 0.050 were shown in bold