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Table 2 Comparison of embryological outcomes between the control and FCP subgroups

From: Diverse impacts of female chromosomal polymorphisms on assisted reproduction outcomes: a retrospective cohort study

 

EMM ± SEM

Coefficient (95% CI)

Adjusted P value

Oocytes retrieved

Control

12.1 ± 0.1

Ref.

Ref.

qh+

11.5 ± 0.4

−0.59(−1.30 ~ 0.12)

0.103

pstk+

12.4 ± 0.4

0.35(−0.41 ~ 1.11)

0.363

inv(9)

11.9 ± 0.6

−0.19(−1.41 ~ 1.02)

0.754

multiple

13.0 ± 0.7

0.95(− 0.43 ~ 2.33)

0.175

others

11.9 ± 0.7

−0.20(− 1.65 ~ 1.24)

0.783

Normal fertilization rate (%)

Control

60.6 ± 0.2

Ref.

Ref.

qh+

61.6 ± 1.3

0.01(−0.02 ~ 0.04)

0.466

pstk+

60.6 ± 1.4

0.00(−0.03 ~ 0.03)

0.974

inv(9)

65.0 ± 2.3

0.04(0.00 ~ 0.09)

0.063

multiple

56.6 ± 2.6

−0.04(−0.09 ~ 0.01)

0.124

others

57.8 ± 2.8

−0.03(− 0.08 ~ 0.03)

0.298

Cleavage rate (%)

Control

97.9 ± 0.1

Ref.

Ref.

qh+

98.2 ± 0.5

0.00(−0.01 ~ 0.01)

0.487

pstk+

97.3 ± 0.5

−0.01(− 0.02 ~ 0.00)

0.258

inv(9)

97.5 ± 0.8

0.00(−0.02 ~ 0.01)

0.595

multiple

98.2 ± 0.9

0.00(−0.02 ~ 0.02)

0.773

others

96.8 ± 1.0

−0.01(− 0.03 ~ 0.01)

0.260

Transplantable embryo rate (%)

Control

54.3 ± 0.3

Ref.

Ref.

qh+

54.2 ± 1.7

0.00(−0.03 ~ 0.03)

0.958

pstk+

52.0 ± 1.8

−0.02(− 0.06 ~ 0.01)

0.205

inv(9)

58.1 ± 2.8

0.04(−0.02 ~ 0.09)

0.183

multiple

49.4 ± 3.2

−0.05(− 0.11 ~ 0.01)

0.128

others

58.5 ± 3.4

0.04(−0.03 ~ 0.11)

0.222

  1. FCP female chromosomal polymorphism, EMM estimated marginal mean, SEM standard error of the means, CI confidence interval, Ref reference
  2. The EMMs, coefficients with their corresponding 95% CIs, and adjusted P values were calculated using generalized linear regression models. The embryological outcomes were adjusted for AFC, diminished ovarian reserve, and paternal factor, except that the oocytes retrieved were adjusted only for AFC and diminished ovarian reserve