History indicated (TVC I, n = 94) | Ultrasound indicated (TVC II, n = 79) | Clinically indicated (TVC III, n = 20) | Abdominal cerclage (n = 10) | p-value | ||
---|---|---|---|---|---|---|
Pre-operative | ||||||
Asymptomatic presentation | 90 (96) | 57 (72) | 14 (70) | 10 (100) | 0.000* | |
Presentation with vaginal bleeding | 3 (3) | 2 (3) | 4 (20) | 0 (0) | 0.005* | |
Pres. with abdominal discomfort | 0 (0) | 20 (25) | 3 (15) | 0 (0) | 0.000* | |
TVU cxl (mm) | 36.0 ± 7.4 | 14.9 ± 7.1 | 0.0 ± 0.0 | 23.1 ± 6.8 | 0.000* | |
TVU funnel length (mm) | 0.1 ± 0.9 | 10.5 ± 10.9 | 25.9 ± 11.8 | 0 ± 0.0 | 0.000* | |
TVU sludge | 1 (1) | 25 (33) | 12 (63) | 0 (0) | 0.000* | |
CRP (mg/L) | 8.3 ± 8.3 | 6.1 ± 7.7 | 6.5 ± 5.3 | NA | 0.194 | |
leucocytes (10*9/L) | 9.3 ± 2.6 | 9.9 ± 2.3 | 10.2 ± 2.7 | 8.8 ± 2.4 | 0.500 | |
neutrophils (10*9/L) | 11.9 ± 8.7 | 7.5 ± 2.2 | 7.2 ± 2.4 | 6.2 ± 2.3 | 0.300 | |
Cerclage placement | ||||||
GA (days) | 96.0 ± 8.7 | 138.4 ± 23.5 | 147.5 ± 15.1 | 92.9 ± 5.6a | 0.000* | |
Multifilament/braided suture | 29 (39) | 29 (39) | 8 (47) | 10 (100) | 0.003* | |
Monofilament/PDS suture | 46 (61) | 36 (55) | 9 (53) | 0 (0) | 0.003* | |
Peroperative antibiotics | 61 (68) | 57 (76) | 17 (85) | 9 (90) | 0.209 | |
Peroperative tocolysis | 50 (56) | 53 (69) | 14 (74) | 8 (80) | 0.143 | |
General anesthesia | 9 (11) | 5 (7) | 2 (12) | 10 (100) | 0.000* | |
Spinal anesthesia | 54 (67) | 50 (69) | 12 (71) | 0 (0) | 0.000* | |
Epidural anesthesia | 18 (22) | 18 (25) | 3 (18) | 0 (0) | 0.342 | |
Peroperative complications | 0 (0.0) | 0 (0) | 0 (0) | 0 (0) | NA | |
Maternal and neonatal outcomes | ||||||
Postoperative CxL (mm) | 33.9 ± 8.6 | 25.0 ± 8.4 | 17.5 ± 9.9 | 30.8 ± 6.3 | 0.000* | |
Postoperative complications | 9 (10) | 2 (3) | 4 (20) | 1 (10) | 0.055 | |
Displacement | 3 (3) | 2 (3) | 1 (5) | 1 (10) | 0.648 | |
PROM | 11 (12) | 14 (18) | 5 (25) | 0 (0) | 0.200 | |
GA at delivery (weeks and days) | 36w1d ± 40d | 35w2d ± 39d | 28w3d ± 49d | 36w6d ± 3d | 0.000* | |
SDI (days) | 144.7 ± 34.3 | 98.1 ± 38.1 | 47.9 ± 47.9 | NA | 0.000* | |
PTB < 37w | 26 (28) | 33 (42) | 16 (84) | 4 (40) | 0.000* | |
PTB < 34w | 20 (22) | 18 (23) | 14 (74) | 0 (0) | 0.000* | |
PTB < 32w | 14 (15) | 16 (21) | 12 (63) | 0 (0) | 0.000* | |
PTB < 28w | 10 (11) | 10 (13) | 11 (58) | 0 (0) | 0.000* | |
PTB < 24w | 7 (8) | 6 (8) | 7 (35) | 0 (0) | 0.000* | |
Birthweight (g)b | 2970 ± 940 | 2687 ± 918 | 1622 ± 1211 | 2793 ± 366 | 0.000* | |
Early neonatal deathc | 0 (0) | 0 (0) | 4 (20) | 0 (0) | 0.000* | |
Alive at discharge | 87 (93) | 71 (90) | 8 (42) | 10 (100) | 0.000* | |
No neonatal complications | 56 (60) | 39 (50) | 4 (21) | 5 (5) | 0.022* |