Controls | IADPSG | NICE | |||||||
---|---|---|---|---|---|---|---|---|---|
Untreated | Treated | Untreated | Treated | ||||||
pª | pb | pª | pb | ||||||
N (%) | 3031 (61.4) | 509 (10.3) | 1292 (26.2) | 166 (3.4) | 612 (12.4) | ||||
Maternal age, years, mean (SD) | 29.4 (5.29) | 30.1 (5.49) | 0.009 | 30.5 (5.56) | 0.157 | 30.0 (5.35) | 0.127 | 30.8 (5.74) | 0.110 |
Pre-pregnancy BMI, kg/m2, mean (SD) | 25.6 (4.47) | 27.3 (5.21) | < 0.001 | 28.4 (5.93) | < 0.001 | 25.9 (5.06) | 0.456 | 28.8 (6.03) | < 0.001 |
BMI categorized, n (%) | < 0.001 | < 0.001 | 0.600 | < 0.001 | |||||
< 18.5 kg/m2 | 61 (2.05) | 5 (1.00) | 16 (1.26) | 5 (3.03) | 6 (1.00) | ||||
18.5–24.9 kg/m2 | 1380 (46.3) | 180 (36.1) | 376 (29.6) | 72 (43.6) | 171 (28.6) | ||||
25.0–29.9 kg/m2 | 1092 (36.6) | 190 (38.1) | 425 (33.5) | 58 (35.2) | 185 (30.9) | ||||
30.0–34.9 kg/m2 | 341 (11.4) | 80 (16.0) | 283 (22.3) | 21 (12.7) | 144 (24.1) | ||||
≥ 35.0 kg/m2 | 107 (3.59) | 44 (8.82) | 170 (13.4) | 9 (5.45) | 92 (15.4) | ||||
Parity, n (%) | |||||||||
Primiparity | 1461 (48.2) | 213 (41.8) | 0.008 | 483 (37.4) | 0.086 | 83 (50.0) | 0.690 | 242 (39.5) | 0.017 |
P1 | 932 (30.7) | 162 (31.8) | 0.641 | 434 (33.6) | 0.505 | 39 (23.5) | 0.056 | 198 (32.4) | 0.029 |
P2 | 382 (12.6) | 74 (14.5) | 0.252 | 205 (15.9) | 0.515 | 28 (16.9) | 0.120 | 88 (14.4) | 0.461 |
P3 | 121 (4.0) | 35 (6.9) | 0.004 | 86 (6.7) | 0.917 | 10 (6.0) | 0.222 | 42 (6.9) | 0.732 |
P4 or more | 135 (4.5) | 25 (4.9) | 0.730 | 84 (6.5) | 0.228 | 6 (3.6) | 0.703 | 42 (6.9) | 0.146 |
Smoking during pregnancy, n (%) | 366 (12.1) | 65 (12.8) | 0.770 | 214 (16.6) | 0.042 | 16 (9.6) | 0.333 | 106 (17.3) | 0.015 |
Socioeconomic status, n (%) | 0.885 | 0.267 | 0.033 | 0.328 | |||||
Upperwhite-collar worker | 536 (17.7) | 85 (16.7) | 0.615 | 195 (15.1) | 0.427 | 17 (10.2) | 0.015 | 93 (15.2) | 0.131 |
Lowerwhite-collar worker | 1017 (33.6) | 167 (32.8) | 0.761 | 439 (34.0) | 0.658 | 56 (33.7) | 1.000 | 210 (34.3) | 0.927 |
Blue-collar worker | 399 (13.2) | 68 (13.4) | 0.944 | 211 (16.3) | 0.129 | 31 (18.7) | 0.047 | 99 (16.2) | 0.482 |
Other | 519 (17.1) | 93 (18.3) | 0.527 | 207 (16.0) | 0.261 | 30 (18.1) | 0.833 | 93 (15.2) | 0.401 |
OGTT performed < 24 weeks | 331 (10.9) | 119 (23.3) | < 0.001 | 403 (31.2) | < 0.001 | 38 (22.9) | < 0.001 | 204 (33.3) | 0.010 |
OGTT performed c / abnormal d, weeks (SD) | 26.7 (3.70) c | 25.8 (5.06) d | < 0.001 | 24.7 (6.48) d | < 0.001 | 26.7 (4.81) d | 0.999 | 24.9 (6.56) d | < 0.001 |
Insulin treatment, n (%) | - | - | - | 135 (10.4) | < 0.001 | 3 (1.8) | < 0.001 | 86 (14.1) | |
Caesarean section, n (%) | 453 (14.9) | 98 (19.3) | 0.015 | 271 (21.0) | 0.437 | 32 (19.3) | 0.148 | 136 (22.2) | 0.457 |
Maternal hypertension, n (%) | 225 (7.4) | 49 (9.6) | 0.089 | 151 (11.7) | 0.213 | 16 (9.6) | 0.364 | 82 (13.4) |