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Table 5 Main factors affecting obstetric and neonatal complications

From: Comparison of pregnancy outcomes among patients of different ages who underwent frozen-thawed high-quality single blastocyst transfer

Factors

Univariable

Multivariable

OR (95% CI)

P value

OR (95% CI)

P value

Infertility duration (year)

    

< 3

Ref

   

≥ 3

1.071(0.708–1.619)

0.746

  

BMI(kg/m2)

    

< 18.5

Ref

   

18.5 ≤ BMI < 24

1.646(0.890–3.044)

0.112

1.612(0.870–2.986)

0.129

24 ≤ BMI < 28

2.353(1.147–4.826)

0.020*

2.258(1.098–4.646)

0.027*

≥ 28

3.429(1.258–9.345)

0.016*

3.431(1.255–9.381)

0.016*

Female age(year)

    

< 30

Ref

   

30 ≤ Age < 35

1.048(0.686–1.602)

0.829

  

35 ≤ Age ≤ 37

1.524(0.842–2.759)

0.164

  

37< Age ≤ 40

0.780(0.357–1.706)

0.535

  

Male age(year)

    

< 30

Ref

   

30 ≤ Age < 35

1.144(0.688–1.901)

0.605

  

35 ≤ Age < 40

0.857(0.479–1.531)

0.601

  

≥ 40

1.083(0.518–2.263)

0.832

  

Infertility type

    

Primary infertility

Ref

   

Secondary infertiliy

1.146(0.780–1.685)

0.487

  

Transplant cycle

    

First cycle

Ref

   

Second cycle

1.526(1.021–2.279)

0.039*

1.495(0.997–2.241)

0.052

PCOS

    

No

Ref

   

Yes

1.327(0.843–2.088)

0.221

  

Endometriosis

    

No

Ref

   

Yes

1.858(0.727–4.752)

0.196

  

Diabetes

    

No

Ref

   

Yes

3.406(0.475–24.401)

0.223

  

Hypertension

    

No

Ref

   

Yes

0.672(0.078-5.800)

0.718

  

Thyroid disease

    

No

Ref

   

Yes

2.284(0.635–8.212)

0.206

  

Number of births

    

0

Ref

   

1–2

0.958(0.630–1.458)

0.842

  

≥ 3

0.918(0.740–1.326)

0.956

  

Number of miscarriages

    

0

Ref

   

1–2

1.222(0.815–1.832)

0.331

  

≥ 3

1.398(0.743–2.629)

0.298

  

Number of pregnancies

    

0

Ref

   

1–2

1.049(0.693–1.587)

0.822

  

≥ 3

1.371(0.792–2.372)

0.260

  

Number of early spontaneous abortion

    

0

Ref

   

1

1.572(0.947–2.610)

0.080

  

2

1.475(0.632–3.444)

0.368

  

Male smoking history

    

No

Ref

   

Yes

1.110(0.664–1.855)

0.690

  

Endometrial thickness (mm)

    

< 8

Ref

   

8–12

1.182(0.807–1.731)

0.391

  

> 12

0.481(0.107–2.159)

0.340

  
  1. BMI Body Mass Index, PCOS Polycystic Ovary Syndrome
  2. *P < 0.05 was statistical significance