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Table 4 Main factors affecting adverse pregnancy outcomes

From: Comparison of pregnancy outcomes among patients of different ages who underwent frozen-thawed high-quality single blastocyst transfer

Factors

Univariable

Multivariable

 

OR (95% CI)

P value

OR (95% CI)

P value

Infertility duration (year)

    

< 3

Ref

   

≥ 3

1.180(0.895–1.556)

0.241

  

BMI(kg/m23)

    

< 18.5

Ref

   

18.5 ≤ BMI < 24

1.621(1.034–2.541)

0.035*

1.544(0.982–2.428)

0.060

24 ≤ BMI < 28

1.925(1.133–3.269)

0.015*

1.856(1.089–3.163)

0.023*

≥ 28

2.026(0.940–4.366)

0.072

2.082(0.965–4.494)

0.062

Female age(year)

    

< 30

Ref

   

30 ≤ Age < 35

1.028(0.748–1.411)

0.867

1.023(0.743–1.407)

0.891

35 ≤ Age ≤ 37

1.361(0.869–2.131)

0.178

1.316(0.837–2.069)

0.235

37< Age ≤ 40

1.649(1.025–2.653)

0.039*

1.630(1.010–2.633)

0.046*

Male age(year)

    

< 30

Ref

   

30 ≤ Age < 35

0.747(0.512–1.090)

0.131

  

35 ≤ Age < 40

1.138(0.764–1.694)

0.525

  

≥ 40

1.204(0.722–2.009)

0.476

  

Infertility type

    

Primary infertility

Ref

   

Secondary infertiliy

1.021(0.771–1.351)

0.886

  

Transplant cycle

    

First cycle

Ref

   

Second cycle

1.148(0.851–1.549)

0.367

  

PCOS

    

No

Ref

   

Yes

1.200(0.859–1.676)

0.285

  

Endometriosis

    

No

Ref

   

Yes

0.502(0.186–1.350)

0.172

  

Diabetes

    

No

Ref

   

Yes

1.020(0.186–5.601)

0.982

  

Hypertension

    

No

Ref

   

Yes

1.020(0.253–4.108)

0.978

  

Thyroid disease

    

No

Ref

   

Yes

1.020(0.346–3.012)

0.971

  

Number of births

    

0

Ref

   

1–2

1.050(0.774–1.424)

0.754

  

≥ 3

2.076(0.290-14.841)

0.467

  

Number of miscarriages

    

0

Ref

   

1–2

1.170(0.872–1.569)

0.296

  

≥ 3

0.990(0.604–1.621)

0.967

  

Number of pregnancies

    

0

Ref

   

1–2

1.020(0.757–1.376)

0.895

  

≥ 3

0.968(0.635–1.475)

0.879

  

Number of early spontaneous abortion

    

0

Ref

   

1

1.187(0.807–1.745)

0.383

  

2

1.614(0.897–2.902)

0.110

  

Male smoking history

    

No

Ref

   

Yes

1.293(0.899–1.858)

0.165

  

Endometrial thickness (mm)

    

< 8

Ref

   

8–12

0.890(0.603–1.314)

0.559

  

> 12

1.190(0.557–2.543)

0.654

  
  1. BMI Body Mass Index, PCOS Polycystic Ovary Syndrome
  2. *P < 0.05 was statistical significance