Outcomes | № of participants (studies) Follow-up | Certainty of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
---|---|---|---|---|---|
Risk with ECC | Risk difference with DCC | ||||
Neonatal hypoglycaemia | 446 (6 RCTs) | ⨁⨁◯◯ Lowa,b | RR 0.87 (0.58 to 1.30) | 207 per 1,000 | 27 fewer per 1,000 (87 fewer to 62 more) |
Length of hospital stay | 2082 (16 RCTs) | ⨁⨁◯◯ Lowc,d | - | The mean length of hospital stay was 24.5 days | MD 0.19 days shorter (0.59 lower to 9.07 higher) |
Breastfeeding at discharge | 1564 (5 RCTs) | ⨁⨁◯◯ Lowa,b | RR 1.04 (0.99 to 1.09) | 711 per 1,000 | 28 more per 1,000 (7 fewer to 64 more) |
NICU Admission for hypoglycaemia | 344 (1 RCT) | ⨁⨁◯◯ Lowe | RR 1.95 (0.18, 21.35) | 6 per 1,000 | 6 fewer per 1,000 (6 fewer to 6 fewer) |
Severe hypoglycaemia | 80 (1 RCT) | ⨁⨁◯◯ Lowe | RR 0.20 (0.01, 4.04) | 50 per 1,000 | 50 fewer per 1,000 (50 fewer to 50 fewer) |
Receipt of treatment for hypoglycaemia | 80 (1 RCT) | ⨁⨁◯◯ Lowe | RR 0.14 (0.01, 2.68) | 75 per 1,000 | 75 fewer per 1,000 (75 fewer to 75 fewer) |