Reciprocal translocation | Robertsonian translocation | Inversion | complex BCR | chi-q/Z | P-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Male | Female | Total | Male | Female | Total | Male | Female | Total | ||||
Female age (y)§ | 30(28–33) | 30(28–32) | 30(28–32) | 31(29–34) | 30(28–33) | 31(28.5–33)* | 32(26.25–34) | 30.5(28.75–34) | 31 (27–34) | 30 (28–32) | 6.352 | 0.096 |
No of miscarriage before PGT§ | 1(0–2) | 1(0–2) | 1(0–2) | 0(0–1) | 1(0–2) | 0(0–1)* | 0(0–2) | 1(0–2) | 1(0–2) | 1(0–2) | 9.594 | 0.022# |
Euploid rate in each PGT cycle§ | 0.25 (0.00–0.50) | 0.25 (0.00–0.50) | 0.25 (0.00–0.50) | 0.50 (0.27–0.71) | 0.40 (0.17–0.60) | 0.50* (0.21–0.67) | 0.54 (0.23–0.96) | 0.50 (0.13–1.00) | 0.50 (0.19–1.00) | 0.50 (0.30–0.59) | 67.771 | 0.000#& |
Euploid rate in total | 30.47% (422/1385) | 29.78% (464/1558) | 30.11% (886/2943) | 51.03% (247/484) | 40.63% (180/443) | 46.06% (427/927)* | 61.32% (65/106) | 53.51% (61/114) | 57.27% (126/220) | 46.15% (18/39) | 130.326 | 0.000#&∋ |
Abnormalities associated with TC | 71.24% (686/963) | 76.87% (841/1094) | 74.23% (1527/2057) | 45.15% (107/237) | 63.12% (166/263) | 54.60%* (273/500) | 31.71% (13/41) | 30.19% (16/53) | 30.85% (29/94) | 85.71% (18/21) | 141.813 | 0.000#&∋Δ |
Abnormalities associated with both TC and other chromosomes | 29.88% (205/686) | 31.51% (265/841) | 30.78% (470/1527) | 36.45% (39/107) | 33.73% (56/166) | 34.80% (95/273) | 76.92% (10/13) | 25% (4/16) | 48.28% (14/29) | 22.22% (4/18) | 4.921 | 0.178 |
Abnormalities unrelated to TC | 20% (277/1385) | 16.24% (253/1558) | 18.01% (530/2943) | 26.86% (130/484) | 21.90% (97/443) | 24.49% (227/927) | 26.42% (28/106) | 32.46% (37/114) | 29.55% (65/220) | 7.69% (3/39) | 35.206 | 0.000&∋£ |
Mosaic rate | 4.26% (59/1385) | 3.40% (53/1558) | 3.81% (112/2943) | 5.37% (26/484) | 5.64% (25/443) | 5.50% (51/927) | 5.66% (6/106) | 7.89% (9/114) | 6.82% (15/220) | 0 (0/39) | 0.568 | 0.753 |
Live birth in each PGT cycle | ||||||||||||
One transplant | 51.56% (116/225) | 57.83% (133/230) | 55.96% (249/445) | 55% (55/100) | 61.90% (52/84) | 58.15% (107/184) | 45% (9/20) | 38.10% (8/21) | 41.46% (17/41) | 57.14% (4/7) | 3.858 | 0.271 |
Two transplant | 45.83% (22/48) | 42.42% (14/33) | 44.44% (36/81) | 45% (9/20) | 39.13% (9/23) | 41.86% (18/43) | 40% (2/5) | 60% (3/5) | 50% (5/10) | 100% (2/2) | 2.399 | 0.506 |
Three transplant | 0 (0/4) | 50% (3/6) | 30% (3/10) | 50% (3/6) | 100% (3/3) | 66.67% (6/9) | 100% (2/2) | 0 | 100% (2/2) | 0 | 4.063 | 0.120 |