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Table 2 Conception and pregnancy loss before and after metroplasty

From: Metroplasty increases the take-home baby rate by reducing pregnancy loss without changing the chance of conception in women with septate uterus: a retrospective, single-center, observational study

 

Abdominal metroplasty (ABM)

Transcervical metroplasty (TCM)

Total

Outcomes

Pre-surgery

Post-surgery

RR$

[95% CI]

p value$

Pre-surgery

Post-surgery

RR$

[95% CI]

p value$

Pre-surgery

Post-surgery

RR$

[95% CI]

p value$

Total number of women (n)

17

17

  

10

10

  

27

27

  

Per conception analysis

Total number of conception

(% conception)

42

(100%)

22

(100%)

  

8

(100%)

11 (100%)

  

50

(100%)

33

(100%)

  

Pregnancy loss

(% conception)

39

(93%)

6

(27%)

0.29

[0.15–0.58]

< 0.0001

8

(100%)

1

(9%)

0.09

[0.01–0.59]

< 0.0001

47

(94%)

7

(21%)

0.23

[0.12–0.44]

< 0.0001

Miscarriage (< 22 weeks)

36

5

  

6

1

  

42

6

  

Late pregnancy loss (≥ 22 weeks)

3

1

  

2

0

  

5

1

  

Take-home baby

(% conception)

3

(7%)

16

(72%)

10.18

[3.32–31.20]

< 0.0001

0

(0%)

10

(91%)

> 10.00

< 0.0001

3

(6%)

26

(79%)

13.13

[4.32–39.90]

< 0.0001

First baby

2

12

  

0

6

  

2

18

  

Second baby

1

4

  

0

3

  

1

7

  

Third baby

0

0

  

0

1

  

0

1

  

Per patient analysis

Women with ≥ 1 conception

(% total women)

13

(76%)

14

(83%)

1.08

[0.76–1.52]

n.s.

7

(70%)

6

(60%)

0.86

[0.45–1.34]

n.s

20

(74%)

20

(74%)

1.00

[0.73–1.37]

n.s.

Women with pregnancy loss

(per conceived women)

13

(100%)

5

(36%)

0.36

[0.18–0.72]

< 0.001

7

(100%)

1

(17%)

0.17

[0.03-1.00]

< 0.01

20

(100%)

6

(30%)

0.30

[0.15–0.59]

< 0.0001

Women with ≤ 21-week miscarriage

(% conceived women)

12

(92%)

4

(29%)

0.31

[0.13–0.72]

< 0.01

5

(50%)

1

(10%)

0.20

[0.03–1.42]

n.s

17

(85%)

5

(25%)

0.29

[0.13–0.64]

< 0.001

Women with ≥ 22-week pregnancy loss

(% conceived women)

3 (23%)

1 (7%)

0.31

[0.04–2.61]

n.s.

2 (20%)

0 (0%)

0.00

n.s

5 (25%)

1

(5%)

0.20

[0.02–1.56]

n.s.

Women with ≥ 22-week pregnancy

(% conceived women)

4 (31%)

13 (93%)

3.02

[1.32–6.91]

< 0.01

2 (29%)

6 (100%)

3.50

[1.08–11.29]

< 0.05

6 (30%)

19 (95%)

3.17

[1.61–6.23]

< 0.0001

Women with ≥ 1 take-home baby

(% total women)

2 (12%)

12 (71%)

6.00

[1.58–22.86]

< 0.01

0 (0%)

6 (60%)

≥ 10.00

< 0.01

2 (7%)

18 (67%)

9.00

[2.31–35.07]

< 0.0001

  1. * All women with or without an experience of pregnancy loss were included
  2. # Only women who had experienced  1 pregnancy loss were included
  3. $The independence of conception before and after surgery was evaluated using the chi-square test
  4. RR, relative risk; 95% CI, 95% confidence interval