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Table 3 Comparison of mental health outcomes at 36 weeks’ gestation

From: Do glycaemic treatment targets affect the perinatal mental health status of women with gestational diabetes? – Data from the TARGET Trial

Outcome

Tight glycaemic targets

Less-tight glycaemic targets

Relative risk or mean difference (95% CI)

N

n (%) or mean ± SD

N

n (%) or mean ± SD

Unadjusted

p-value

Adjustedb

p-value

Poor mental health compositea

168

39 (23.2)

153

26 (17.0)

1.25 (0.69, 2.27)

0.45

1.07 (0.58, 1.95)

0.84

Anxiety (STAI > 15)

171

23 (13.5)

156

27 (17.3)

0.87 (0.45, 1.69)

0.67

0.85 (0.44, 1.62)

0.62

STAI score

171

10.6 ± 3.4

156

10.9 ± 3.6

0.01 (-0.89, 0.91)

0.99

0.00 (-0.80, 0.81)

0.99

Depression (EPDS > 12)

180

16 (8.9)

154

11 (7.1)

1.36 (0.55, 3.35)

0.51

1.10 (0.43, 3.83)

0.85

EPDS score

180

6.4 ± 4.2

154

6.4 ± 4.5

0.01 (-1.11, 1.12)

0.99

-0.12 (0.90, 0.66)

0.77

Poor mental HRQoL (MCS < 40)

175

26 (14.9)

157

17 (10.8)

1.13 (0.54, 2.37)

0.74

1.05 (0.50, 2.20)

0.90

SF-36 scores:

 General health

178

71.2 ± 17.8

157

71.9 ± 17.1

0.48 (-4.01, 4.96)

0.83

-0.37 (-3.79, 3.04)

0.83

 Mental health

182

69.0 ± 12.0

157

70.6 ± 10.5

-1.16 (-4.06, 1.74)

0.43

-0.20 (-2.62, 2.23)

0.87

 Physical functioning

182

58.1 ± 22.1

157

59.4 ± 22.3

-1.96 (-7.62, 3.70)

0.50

-0.86 (-5.80, 4.08)

0.73

 Social functioning

183

75.0 ± 22.6

157

76.6 ± 21.4

-2.26 (-7.91, 3.39)

0.43

-1.03 (-5.79, 3.74)

0.67

 Role physical

182

47.0 ± 42.1

157

44.6 ± 40.8

-7.0 (-11.30, 9.90)

0.90

2.53 (-6.92, 11.98)

0.60

 Role emotional

182

77.2 ± 37.1

157

77.9 ± 35.4

0.08 (-9.23, 9.40)

0.99

1.44 (-6.88, 9.75)

0.73

 Bodily pain

183

60.3 ± 22.4

157

60.1 ± 20.7

-0.27 (-5.83, 5.29)

0.92

1.26 (-3.41, 5.93)

0.60

 Vitality

179

55.3 ± 14.3

157

51.2 ± 14.5

2.44 (-1.35, 6.23)

0.21

0.82 (-1.89, 3.53)

0.55

 PCS

175

40.2 ± 8.9

157

40.0 ± 9.2

-2.0 (-2.53, 2.14)

0.87

0.42 (-1.49, 2.33)

0.67

 MCS

175

49.4 ± 7.7

157

49.8 ± 7.1

0.04 (-1.88, 1.96)

0.97

0.20 (-1.36, 1.76)

0.80

  1. Any of anxiety (STAI > 15), vulnerability to depression (EPDS > 12) or poor mental health-related quality of life (SF-36 MCS < 40)
  2. b Adjusted for body mass index, gestational age at oral glucose tolerance test, ethnicity, and history of gestational diabetes
  3. CI confidence interval, EPDS Edinburgh Postnatal Depression Scale, HRQoL health-related quality of life, MCS Mental Component Summary, PCS Physical Component Summary, RR Relative risk, STAI Spielberger State-Trait Anxiety Inventory, SD standard deviation, SF-36 36-Item Short-Form General Health Survey
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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