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Table 3 Side effects and neonatal outcomes

From: Oxytocin infusion for maintenance of uterine tone under prophylactic phenylephrine infusion for prevention of post-spinal hypotension in cesarean delivery: a prospective randomised double-blinded dose-finding study

 

Oxytocin infusion rates

 
 

2.5 IU/h

(n = 25)

5.0 IU/h

(n = 25)

7.5 IU/h

(n = 24)

10.0 IU/h

(n = 25)

P value

Hypertension

0 (0)

0 (0)

1(4)

2 (8)

0.068

Hypotension

5 (20)

5 (20)

5 (21)

3 (12)

0.502

Bradycardia

0 (0)

1 (4)

2 (8)

1 (4)

0.361

Nausea

2 (8)

0 (0)

1 (4)

1 (4)

0.658

Flushing

2(8)

1(4)

2 (8)

3 (12)

0.505

Shivering

0 (0)

0 (0)

0 (0)

1 (4)

0.180

Chest pain

1 (4)

0 (0)

1 (4)

1(4)

0.995

1-min Apgar score

9 (9–10)

9 (9–10)

10 (9–10)

10 (9–10)

0.527

5-min Apgar score

10 (10–10)

10 (10–10)

10 (10–10)

10 (10–10)

0.899

Umbilical arterial pH

7.31(7.28–7.35)

7.31(7.29–7.35)

7.31(7.28–7.33)

7.31(7.29–7.34)

0.989

Umbilical arterial PO2

20.8 ± 4.7

20.4 ± 6.3

22.7 ± 7.0

23.0 ± 7.8

0.384

Umbilical arterial PCO2

45.6 ± 8.6

47.8 ± 6.8

50.4 ± 10.5

51.6 ± 11.1

0.107

Umbilical arterial BE

−2.1(−6.0 - -1.0)

−2.2(−5.6 - -0.6)

−0.9(−4.1–0.4)

−1.2(− 2.5–0.7)

0.131

Umbilical arterial HCO3

23.3 (18.5–25.0)

24.3 (19.5–26.0)

26.0 (22.5–27.4)

25.6 (22.9–27.1)

0.061

Neonatal weight, g

3276 ± 279

3330 ± 380

3317 ± 321

3424 ± 267

0.403

  1. Data shown as number (%), median (quartiles), or mean (SD) as appropriate