Table 4 Association between the IL-13 (rs20541 (G/A) and rs56035208 (G/C)) polymorphisms and preeclampsia risk markers in preeclampsia and control groups

Seizures Present

0 (0)

0 (0)

1 (0.7)

0.9

SeizuresPresent

1 (0.7)

0 (0)

0 (0)

0.97

Absent

1 (0.7)

3 (0.7)

145 (99.3)

Absent

142 (99.3)

4 (100)

3 (100)

Absent

0 (0)

2 (67.7)

51 (34.9)

0.9

Proteinuria Absent

50 (0.35)

0 (0)

3 (100)

0.4

Trace

0 (0)

0 (0)

18 (12.3)

Trace

17 (11.9)

1 (25)

0 (0)

1

1 (100)

1 (33.3)

44(30.1)

1

44 (30)

2 (50)

0 (0)

2

0 (0)

0 (0)

15 (10.3)

2

15 (10)

0 (0)

0 (0)

3

0 (0)

0 (0)

14 (9.6)

3

13 (9.1)

1 (25)

0 (0)

4

0 (0)

0 (0)

4 (2.7)

4

4 (2/8)

0 (0)

0 (0)

Edema Absent

0 (0)

1 (33.3)

22 (15.1)

0.02

Edema Absent

21 (14.7)

1 (0.25)

1 (33.3)

0.831

1

0 (0)

1 (33.3)

90 (61.6)

1

88 (61.5)

2 (50)

1 (33.3)

2

0 (0)

1 (33.3)

24 16.4

2

23 (16.1)

1 (0.25)

1 (33.3)

3

1 (100)

0 (100)

10 (6.8)

3

11 (7.7)

0 (0)

0 (0)

Diabetes Present

0 (0)

0 (0)

9 (6.2)

0.8

Diabetes Present

9 (6.3)

0 (0)

0 (0)

0.9

Absent

1 (100)

3 (100)

137 (93.8)

Absent

134 (93.7)

4 (100)

3 (100)

Multipara Primary

2 (40)

3 (50)

133 (46)

0.9

Multipara Primary

134 (46.4)

4 (66.7)

0 (0)

0.9

Multiple

3 (60)

3 (50)

156 (54)

Multiple

155 (53.6)

2 (33.3)

5 (100)

Hypertension Mild

1 (100)

2 (66.7)

113 (77.4)

0.831

Hypertension Mild

111 (33.3)

2 (50)

3 (100)

0.831

Moderate

0 (0)

1 (33.3)

25 (17.1)

Moderate

25 (17.5)

1 (25)

0 (0)

Severe

0 (0)

0 (0)

8 (5.5)

Severe

7 (4.9)

1 (25)

0 (0)

Gravida Present

0 (0)

0 (0)

6 (4.1)

0.9

Gravida Present

6 (4.2)

0 (0)

0 (0)

0.9

Absent

1 (100)

3 (100)

140 (95.3)

Absent

137 (95.8)

4 (100)

3 (99.3)

Hyperthyroidism Present

0 (0)

0 (0)

17 (11.6)

0.9

Hyperthyroidism Present

17 (11.9)

0 (0)

0 (0)

0.9

Absent

1 (100)

3 (100)

129 (88/4)

Absent

126 (88.1)

4 (100)

3 (100)

HELLP syndrome Present

0 (0)

0 (0)

1 (7)

0.9

HELLP syndrome Present

1 (0.7)

0 (0)

0 (0)

0.9

Absent

1 (100)

3 (100)

145 (99.3)

Absent

142 (99.3)

4 (100)

3 (100)

History of abortion Present

1 (100)

1 (33.3)

28 (19.2)

0.9

History of abortion Present

30 (21.7)

0 (0)

0 (0)

0.9

Absent

0 (0)

2 (66.7)

118 (80.8)

Absent

113 (79.3)

4 (100)

3 (100)

History of preeclampsia Present

0 (0)

0 (0)

13 (8.9)

0.9

History of preeclampsia Present

12 (8.4)

0 (0)

1 (100)

0.9

Absent

1 (100)

3 (100)

133 (91.1)

Absent

113 (91.3)

4 (100)

2 (66)

Maternal drinking Yes

1 (100)

0 (0)

0 (0)

0.062

Maternal drinking Yes

1 (100)

0 (0)

0 (0)

0.002

No

22 (14.8)

59 (39.6)

68 (45.6)

No

11 (7.4)

52 (34.9)

86 (57.7)

Maternal smoking Yes

5 (38.46)

4 (30.76)

4 (30.76)

0.539

Maternal smoking Yes

10 (76.92)

3 (23.07)

0 (0)

0.63

No

64 (46.71)

47 (34.30)

26 (18.97)

No

92 (67.15)

38 (27.73)

7 (5.10)

Socioeconomic position High

6 (75)

0 (0)

2 (25)

0.209

Socioeconomic position High

6 (75)

2 (25)

0 (0)

0.272

Middel

50 (43.10)

41 (35.34)

25 (21.55)

Middel

81 (69.8)

28 (24.1)

7 (6)

Low

13 (50)

10 (38.46)

3 (53.11)

Low

15 (57.7)

11 (42.3)

0 (0)

Maternal BMI <18.5

6 (54.54)

4 (36.36)

1 (9.09)

0.419

Maternal BMI <18.5

15 (60)

9 (36)

1 (4)

0.739

18.5–24.9

16 (64)

6 (24)

3 (12)

18.5–24.9

18 (78.26)

4 (17.39)

1 (4.35)

25–29.9

39 (42.86)

31 (34.07)

21 (23.07)

25–29.9

60 (65.93)

26 (28.75)

5 (5.49)

≥30

8 (34.78)

10 (43.48)

5 (21.74)

≥30

9 (81.82)

2 (18.18)

0 (0)

Birth weight >2500 g

62 (43.97)

49 (34.75)

30 (21.27)

0.11

Birth weight >2500 g

96 (68.01)

7 (4.96)

0.75

38 (26.95)

<2500g

7 (77.77)

2 (22.22)

0 (0)

<2500g

6 (66.66)

3 (33.33)

0 (0)

Maternal age <20

1 (12.5)

5 (62.5)

2 (25)

0.136

Maternal age <20

1 (12.5)

3 (37.5)

4 (50)

0.816

20–29

16 (13.8)

41 (35.3)

59 (50.9)

20–29

10 (8.6)

38 (32.8)

68 (58.6)

≥30

6 (23.1)

13 (50)

7 (26.9)

≥30

1 (3.8)

11 (42.3)

14 (53.8)