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Table 2 Determinants of fetal growth (1,168 women delivered between 01/01/2012 and 31/12/2018 in Jean Verdier University hospital, France)

From: Impact of experiencing multiple vulnerabilities on fetal growth and complications in women with hyperglycemia in pregnancy

Parameters

Small-for-gestational-agea N = 133 (11.4%)

Appropriate-for-gestational-age N = 893 (76.5%)

Large-for-gestational-agea N = 142 (12.2%)

P

Indicators of socioeconomic vulnerability

 Psychosocial deprivation

36.4 ± 21.1

36.1 ± 21.3

35.9 ± 20.7

 

 French language proficiency

30 (26.3)

228 (29.4)

21 (17.1)

0.00

 Food insecurity

21 (20.8)

120 (17.8)

18 (16.2)

0.67

Medical history and glycemic figures

 Age (years)

32.8 ± 5.2

32.7 ± 5.3

32.5 ± 5.5

0.89

 Body mass index (kg/m2)

26.1 ± 5.6

26.7 ± 5.2

29.3 ± 5.8

0.00

 Obesity

23 (17.6)

231 (26.0)

60 (42.3)

0.00

 Hypertension before pregnancy

2 (1.5)

12 (1.3)

2 (1.4)

0.30

 Family history of diabetes

43 (32.3)

296 (33.1)

61 (43.0)

0.06

Smoking before pregnancy

13 (9.8)

75 (8.4)

9 (6.3)

0.09

Parity, number of children

1.9 ± 1.2

2.3 ± 1.3

2.6 ± 1.1

0.00

History of HIP

0.00

 1st child

70 (52.6)

274 (30.7)

24 (16.9)

 no

42 (31.6)

488 (54.6)

71 (50.0)

 yes

21 (15.8)

131 ((14.7)

47 (33.1)

History of macrosomia

0.00

 1st child

70 (52.6)

274 (30.7)

24 (16.9)

 no

62 (46.6)

579 (64.8)

90 (63.4)

 yes

1 (0.8)

40 (4.5)

28 (19.7)

History of fetal death

0.76

 1st pregnancy

37 (27.8)

165 (18.5)

16 (11.3)

 no

91 (68.4)

700 (78.4)

120 (84.5)

 yes

5 (3.8)

28 (3.1)

6 (4.2)

Screening for HIP before 22 WG

0.04

 Fasting plasma glucose (mmol/L)

5.0 ± 0.5

5.2 ± 0.9

5.1 ± 0.5

OGTT at 22 WG and after

 Fasting plasma glucose (mmol/L)

5.0 ± 0.7

5.1 ± 0.7

5.1 ± 0.7

0.14

 1H-post OGTT glucose (mmol/L)

9.8 ± 2.1

9.4 ± 2.0

9.5 ± 2.0

0.28

 2H-post OGTT glucose (mmol/L)

8.5 ± 2.0

8.1 ± 1.9

8.3 ± 2.2

0.16

    HIP status

43 (32.4)

275 (30.8)

46 (32.4)

0.93

    eGDM

81 (60.9)

562 (62.9)

85 (59.9)

 

    GDM

9 (6.8)

56 (6.3)

11 (7.7)

 

DIP

 Gestational weight gain

8.4 ± 4.8

9.3 ± 5.5

10.3 ± 6.2

0.03

Sociodemographic parameters

 Employment

  Working

50 (37.9)

327 (36.7)

50 (35.2)

0.90

Self-reported region of origin

0.02

 Sub-Saharan Africa

20 (15.2)

141 (15.8)

18 (12.7)

 

 North Africa

35 (26.5)

310 (34.8)

75 (52.8)

 

 Other

10 (7.6)

72 (8.1)

6 (4.2)

 

 Europe

28 (21.2)

173 (19.4)

24 (16.9)

 

 Haiti, French overseas territories

6 (4.5)

43 (4.8)

3 (2.1)

 

 South Asia

33 (25.0)

153 (17.2)

16 (11.3)

 

Health insurance coverage

0.049

 Social Security

45 (52.3)

349 (56.7)

50 (51.0)

 

 Universal health protection

20 (23.3)

149 (24.2)

21 (21.4)

 

 Complementary universal health protection

10 (11.6)

62 (10.1)

21 (21.4)

 

 State medical aid

11 (12.8)

55 (8.9)

6 (6.1)

 

Indicators of socioeconomic vulnerability

 

 Psychosocial deprivation

36.36 ± 21.08

36.09 ± 21.31

35.91 ± 20.76

 

 French language proficiency

30 (26.3)

228 (29.4)

21 (17.1)

0.003

 Food insecurity

21 (20.8)

120 (17.8)

18 (16.2)

0.67

  1. HIP Hyperglycemia in pregnancy, OGTT 75 g oral glucose tolerance test, WG Gestational weeks, eGDM early-diagnosed gestational diabetes mellitus, GDM Gestational diabetes mellitus, DIP Diabetes in pregnancy
  2. aSGA and LGA infant were defined as a birth weight lower than the 10th percentile and greater than the 90th percentile for the standard French population, respectively