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Table 1 Characteristics of the cohort, medical history and glycemic figures, and sociodemographic parameters (1,168 women delivered between 01/01/2012 and 31/12/2018 in Jean Verdier University hospital, France)

From: Impact of experiencing multiple vulnerabilities on fetal growth and complications in women with hyperglycemia in pregnancy

Parameters

N

Total N = 1,168

No psychosocial deprivationa N = 515 (44%)

Psychosocial deprivationa N = 653 (56%)

P

Medical history and glycemic figures

 EPICES Score

1,168

36.1 ± 21.2

16.7 ± 8.2

51.3 ± 15.0

0.00

 Age (years)

1,168

32.7 ± 5.4

32.67 ± 5.4

32.7 ± 5.4

1.00

 Body mass index (kg/m2)

1,168

27.0 ± 5.4

27.0 ± 5.5

27.0 ± 5.3

0.93

 Obesity

1,168

314 (27.0)

14.9 (28.9)

16.5 (25.5)

0.19

 Hypertension before pregnancy

1,168

16 (1.4)

5 (1.0)

11 (1.7)

0.30

 Family history of diabetes

1,168

400 (34.2)

197 (38.3)

203 (31.1)

0.01

 Smoking before pregnancy

1,168

97 (8.3)

56 (10.9)

41 (6.3)

0.00

 Parity (number of children)

1,168

2.3 ± 1.3

2.1 ± 1.1

2.5 ± 1.4

0.00

History of HIP

1,168

   

0.60

 1st child

 

368 (31.5)

189 (36.7)

179 (27.4)

 no

 

601 (51.5)

235 (45.6)

366 (56.0)

 yes

 

199 (17.0)

91 (17.7)

108 (16.5)

History of macrosomia

1,168

   

0.64

 1st child

 

368 (31.5)

189 (36.7)

179 (27.4)

 no

 

731 (62.6)

298 (57.9)

366 (56.0)

 yes

 

69 (5.9)

28 (5.4)

108 (16.5)

History of fetal death

1,168

   

0.84

 1st pregnancy

 

218 (18.7)

105 (20.4)

113 (17.3)

 no

 

911 (78.0)

393 (76.3)

518 (79.3)

 yes

 

39 (3.3)

17 (3.3)

22 (3.4)

Screening for HIP before 22 WG

0.31

 Fasting plasma glucose (mmol/L)

776

5.2 ± 0.8

5.2 ± 0.8

5.2 ± 0.8

OGTT at 22 WG and after

 

 Fasting plasma glucose (mmol/L)

811

5.1 ± 0.7

5.0 ± 0.6

5.2 ± 0.8

0.01

 1H-post OGTT glucose (mmol/L)

752

9.5 ± 2.0

9.5 ± 1.8

9.5 ± 2.1

0.83

 2H-post OGTT glucose (mmol/L)

756

8.2 ± 1.9

8.2 ± 1.8

8.1 ± 2.0

0.54

HIP status

1,168

   

0.67

 eGDM

 

364 (31.2)

164 (31.8)

200 (30.6)

 

 GDM

 

728 (62.3)

321(62.3)

407 (62.3)

 

 DIP

 

76 (6.5)

30 (5.8)

46 (7.0)

 

Sociodemographic parameters

 Employment

0.00

  Working

1,166

427 (36.6)

274 (53.3)

153 (23.5)

 

Self-reported region of origin

1,166

   

0.00

 Sub-Saharan Africa

 

179 (15.4)

40 (7.8)

139 (21.3)

 

 North Africa

 

420 (36.0)

212 (41.2)

208 (31.9)

 

 Other

 

88 (7.5)

41 (8.0)

47 (7.2)

 

 Europe

 

225 (19.3)

155 (30.2)

70 (10.7)

 

 Haiti, French overseas territories

 

52 (4.5)

20 (3.9)

32 (4.9)

 

 South Asia

 

202 (17.3)

46 (8.9)

156 (23.9)

 

Health insurance coverage

799

   

0.00

 Social Security

 

444 (55.6)

261 (71.7)

183 (42.1)

 

 Universal health protection

 

190 (23.8)

44 (12.1)

146 (33.6)

 

 Complementary universal health protection

 

93 (11.6)

54 (14.8)

39 (9.0)

 

 State medical aid

 

72 (9.0)

5 (1.4)

67(15.4)

 

 Poor French language proficiency

1,013

279 (27.5)

60 (13.1)

219 (39.5)

0.00

 Food insecurity

887

159 (17.9)

24 (5.9)

135 (28.2)

0.00

  1. HIP hyperglycemia in pregnancy, OGTT 75 g oral glucose tolerance test, WG Gestational weeks, eGDM early-diagnosed gestational diabetes mellitus, GDM Gestational diabetes mellitus, DIP Diabetes in pregnancy
  2. aPsychosocial deprivation was defined as an EPICES score > 30.17