Table 1 the patients’ baseline characteristics
Case | Basal state | Endocrinological basal value | TUS | pituitary gland MRI | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pregnacy (weeks) | Age (yr) | Symptoms | LT4 (µg/Day) | TSH (µIU/mL) | FT4 (ng/dL) | TgAb (U/mL) | TPOAb (U/mL) | BC (µg/dL) | ACTH (µg/dL) | Internal properties | Estimated weight (g) | ||
Group 1; AI group (n = 4) | |||||||||||||
1 | 11 | 34 | none | 25 | 2.6 | 0.9 | 45.6 | 14.7 | 6 | 28.9 | DP | 33.6 | NA |
2 | 14 | 42 | nausea | none | 4.88 | 0.96 | ≦ 10 | 5 | 10.5 | 5.7 | NP | 6.6 | NA |
3 | 15 | 33 | none | 25 | 1.46 | 1.44 | 1.24 | 1.28 | 10.7 | 22.5 | NP | none | Ratke cyst |
4 | 17 | 31 | nausea | 37.5 | 0.81 | 1.04 | 5.1 | <0.50 | 15.3 | 14.8 | DP | 13.1 | none |
Group 2; hypothyroid group with low basal serum cortisol but pass stimulation test (n = 3) | |||||||||||||
5 | 7 | 22 | fatigue | none | 10.8 | 0.96 | 183 | 1450 | 8 | 10.4 | DP | 20.3 | NA |
6 | 12 | 31 | nausea | none | 5.73 | 1.09 | 2.93 | <0.50 | 12 | 18.9 | NP | 8.1 | pituitary cyst |
7 | 15 | 37 | none | 75 | 1.17 | 1.21 | ≦ 10 | 12.43 | 10.4 | 10.8 | NP | 5.5 | NA |
Group 3; Hypothyroid group with adequate basal serum cortisol (n = 6) | |||||||||||||
8 | 14 | 41 | nausea | 50 | 1.2 | 0.99 | 0.78 | <0.50 | 11.1 | 9 | NP | 8.8 | none |
9 | 16 | 24 | none | 50 | 2.96 | 1.34 | 1.2 | 26.5 | 24.8 | none | DP | 7.9 | none |
10 | 21 | 31 | mild | none | 5.6 | 0.85 | ≦ 10 | 10 | 22.3 | 14.7 | NP | 9.5 | none |
11 | 27 | 34 | none | none | 5.57 | 0.79 | 0.8 | 1.17 | 24.5 | 16.9 | NP | 7.2 | none |
12 | 31 | 35 | nausea | 50 | 1.73 | 0.9 | 0.45 | <0.50 | 27.6 | 12.6 | NP | 7.8 | none |
13 | 33 | 28 | nausea | 37.5 | 2.31 | 1.11 | 1.96 | <0.50 | 21.3 | 9.3 | NP | 7.1 | none |
low basal serum cortisol but refused stimulation test (n = 2) | |||||||||||||
14 | 19 | 29 | hypoglyceimia | 12.5 | 1.8 | 1.08 | 11.5 | 0.61 | 13.4 | 6.3 | NP | 8.1 | NA |
15 | 31 | 34 | nausea | 100 | 0.59 | 1.13 | 88 | 281 | 16.8 | none | NP | 9.7 | none |