Table 4 Univariable analysis of risk factors for neurodevelopmental impairment

Maternal highest education level

 Postgraduate/Bachelor

31 (81.6)

7 (18.4)

Reference

Reference

 Diploma/certificate/secondary

29 (58.0)

21 (42.0)

3.21 [1.19, 8.66]

0.022

Sex

 Female

36 (70.6)

15 (29.4)

Reference

Reference

 Male

26 (66.7)

13 (33.3)

1.20 [0.49, 2.94]

0.691

Child’s age at interview (years)

 0–4.9

18 (81.8)

4 (18.2)

Reference

Reference

 5–9.9

30 (65.2)

16 (34.8)

2.4 [0.69, 8.31]

0.167

 10 + 

14 (63.6)

8 (36.4)

2.6 [0.64, 10.31]

0.183

Donor/recipient status

 Donor

22 (61.1)

14 (38.9)

Reference

Reference

 Recipient

34 (70.8)

14 (29.2)

0.65 [0.26, 1.61]

0.351

 Other

6 (100.0)

0 (0.0)

n/a

n/a

Gestation of laser (weeks)

  < 20

30 (75.0)

10 (25.0)

Reference

Reference

 20 + 

32 (64.0)

18 (36.0)

1.69 [0.67, 4.23]

0.265

Year of laser

 2006–8

8 (72.7)

3 (27.3)

Reference

Reference

 2009–11

13 (54.2)

11 (45.8)

2.26 [0.47, 10.64]

0.304

 2012–14

17 (68.0)

8 (32.0)

1.25 [0.26, 6.03]

0.777

 2015–17

24 (80.0)

6 (20.0)

0.67 [0.13, 3.30]

0.619

Birth gestation

 32–36 weeks

39 (81.2)

9 (18.8)

Reference

Reference

 25–31 weeks

23 (54.8)

19 (45.2)

3.58 [1.39, 9.22]

0.008

Time in special care

  < 4 weeks

32 (91.4)

3 (8.57)

Reference

Reference

 4–12 weeks

21 (58.3)

15 (41.7)

7.62 [1.96, 29.57]

0.003

  > 12 weeks

9 (47.4)

10 (52.6)

11.85 [2.68, 52.44]

0.001

Ventilation required

 No

31 (83.8)

6 (16.2)

Reference

Reference

 Yes

30 (57.7)

22 (42.3)

3.79 [1.35, 10.64]

0.011

Co-multiple survival

 Sole survivor

12 (75.0)

4 (25.0)

Reference

Reference

 Co-twin alive

50 (67.6)

24 (32.4)

1.44 [0.42, 4.94]

0.562

Congenital anomalies

 No

56 (70.9)

23 (29.1)

Reference

Reference

 Yes

6 (54.6)

5 (45.4)

2.03 [0.56, 7.31]

0.279