Table 1 Total registered live births and prenatal diagnostic tests for AMA pregnancies from 2006 to 2019

Registered live births

205,720

203,711

196,486

192,133

166,473

198,348

234,599

194,939

211,399

213,093

207,600

194,616

181,601

175,074

2,775,792

Maternal age ≧ 35

23,920

25,260

26,389

27,683

28,689

39,213

48,653

42,787

48,689

53,076

56,207

56,508

54,406

54,162

585,642

% of maternal age ≧ 35

11.63%

12.40%

13.43%

14.41%

17.23%

19.76%

20.74%

21.95%

23.03%

24.91%

27.07%

29.04%

29.96%

30.94%

21.18%

Total No. invasive prenatal diagnosis

30,302

32,801

33,396

38,632

37,542

48,317

56,117

47,117

51,421

57,471

53,919

46,413

41,520

43,878

618,846

% of total invasive prenatal diagnosis

14.73%

16.10%

17.00%

20.11%

22.55%

24.36%

23.92%

24.17%

24.32%

26.97%

25.97%

23.85%

22.86%

25.06%

22.28%

No. of maternal age≧ 35

21,278

23,628

23,991

27,571

28,024

38,127

45,318

38,921

43,017

48,547

45,929

40,124

35,932

38,456

498,863

% of invasive maternal age≧ 35

88.95%

93.54%

90.91%

99.60%

97.68%

97.23%

93.15%

90.96%

88.35%

91.47%

81.17%

71.00%

66.04%

71.00%

87.22%

Total Trisomy 21

228

182

219

211

211

322

312

321

359

366

361

345

327

333

4097

Registered trisomy 21 TOPs

169

132

173

163

191

291

288

289

334

343

346

331

317

321

3688

Registered trisomy 21 live birth

59

50

46

48

20

31

24

32

25

23

15

14

10

12

409

Total Trisomy 18

42

31

29

32

70

97

97

83

98

112

108

97

102

81

1079

Registered trisomy 18 TOPs

35

29

26

27

68

92

94

82

97

111

107

95

100

80

1043

Registered trisomy 18 live births

7

2

3

5

2

5

3

1

1

1

1

2

2

1

36

Total trisomy 13

9

8

13

7

25

21

19

36

30

33

29

32

28

27

317

Registered trisomy 13 TOPs

9

3

13

6

23

20

19

36

28

32

29

32

28

27

305

Registered trisomy 13 live births

0

5

0

1

2

1

0

0

2

1

0

0

0

0

12