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Table 1 Socio-demographics and past and current obstetric history according to whether women did or did not develop pre-eclampsia (PE). Data are presented as mean ± Standard deviation (SD) or as number (%)

From: Performance of Fetal Medicine Foundation algorithm for first trimester preeclampsia screening in an indigenous south Asian population

Characteristic

No Pre-eclampsia

(n = 1804)

Pre-eclampsia

(n = 59)

p-value

Age (years)

30.89 ± 4.04

31.40 ± 3.63

0.33

Weight (kg)

63.02 ± 10.85

65.47 ± 12.21

0.09

Height (cm)

159.57 ± 5.54

157.57 ± 5.07

0.006

Body Mass Index (kg/m2)

24.70 ± 4.18

26.35 ± 4.63

0.003

Crown Rump Length (mm)

63.61 ± 8.02

62.92 ± 6.22

0.513

Gestational at screening (days)

88.25 ± 4.43

88.12 ± 3.62

0.815

Assisted Conception

95 (5.3%)

2 (3.4%)

0.52

Chronic Hypertension

17 (0.9%)

13 (22.0%)

< 0.001

SLE/APS

6 (0.3%)

0 (0.0%)

0.66

Diabetes Mellitus

47 (2.6%)

6 (10.2%)

0.001

Past Obstetric History

  Nulliparous

1087 (60.3%)

35 (59.3%)

< 0.001

  Parous no previous PE

692 (38.4%)

18 (30.5%)

  Parous with previous PE

25 (1.4%)

6 (10.2%)

Screening Biomarkers

  log10 MAP MoM

−0.0029 ± 0.0307

0.0247 ± 0.0405

< 0.001

  log10 UtAPI MoM

− 0.0146 ± 0.1325

−0.0105 ± 0.1440

0.154

  log10 PAPP-A MoM

−0.0706 ± 0.2550

−0.1520 ± 0.2577

0.016

  log10 PlGF MoM

−0.0608 ± 0.2153

−0.1701 ± 0.2305

0.001

Gestational at Delivery (days)

263.43 ± 30.16

254.83 ± 18.38

0.001

Male

963 (53.4%)

32 (54.2%)

0.897

Birth weight (g)

2933 ± 485

2465 ± 809

< 0.001

  1. Abbreviations:; SLE- Systematic Lupus Erythematosus; Anti Phospholipid Antibody syndrome; MoM – Multiple of Median; MAP- Mean Arterial Pressure; UtAPI – Uterine Artery Pulsatility Index; PAPP-A – Pregnancy Associated Plasma Protein-A; PlGF – Placental Growth Factor