Pregnancy outcomes of Chinese women undergoing IVF with embryonic cryopreservation as compared to natural conception

Table 3 Neonatal outcomes among different infertility etiologies for IVF compared to spontaneous pregnancies in singleton pregnancies

	Control		Ovulation disorder		Tubal disease		Endometriosis		Male infertility		Mixed infertility
Singleton Pregnancies	N	%	N	%	N	%	N	%	N	%	N	%
	6832		271		542		74		267		87
Gestational weeks	38.8±1.5		38.3±1.8*		38.5±1.6*		38.3±1.8^		38.5±1.8^		38.1±1.9*
Preterm birth	355	5.2	25	9.2^	36	6.6	7	9.5	20	7.5	11	12.6^
34≤PTD<37 wk	267	3.9	17	6.3	29	5.4	5	6.8	16	6	9	10.3^
28≤PTD<34 wk	88	1.3	8	3^	7	1.3	2	2.7	5	1.9	2	2.3
Birthweight, g( Mean±SD)	3370±474		3379±580		3382±498		3244±502^		3335±519		3278±518
Birthweight centile(Mean±SD)	57.29±24.81		59.51±26.60		57.29±26.02		51.84±27.97		55.28±26.80		57.37±26.53
< 2500 g	236	3.5	17	6.3^	21	3.9	4	5.4	13	4.9	6	6.9
< 1500 g	38	0.6	4	1.5	3	0.6	0	0	3	1.1	1	1.1
SGA	281	4.1	18	6.6^	21	3.9	7	9.5^	12	4.5	5	5.7
Macrosomia	521	7.6	31	11.4^	64	11.8*	10	13.5	20	7.5	6	6.9
Body length, cm	50.55±41.78		49.85±2.37		50.02±1.88		49.73±2.01		49.92±2.04		49.63±2.12^
1-Minute Apgar score≤7	64	0.9	5	1.8	4	0.7	0	0	4	1.5	4	4.6*
5-Minute Apgar score≤7	10	0.1	1	0.4	3	0.6*	0	0	0	0	0	0
NICU admission	728	10.7	48	17.7*	72	13.3	17	23*	33	12.4	15	17.2^

Note: PTD preterm delivery, SGA small for gestational age( birthweight below the 10th percentile for gestational age); Macrosomia = birth weight ≥ 4000g
Mixed infertility refers to multiple infertility-related diagnosis
Data are presented as means±SDs for continuous variables and n (%) for dichotomous variables. P values were assessed by using the Pearson’s chi-square test, Fisher’s exact test or the t test between each infertility subgroup vs controls ; P ≤ 0.001 = *; P < 0.05 = ^. Nonsignificant numbers have not symbol

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