<35 years of age | ≥ 35 years of age | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Group A | Group B | Group C | Group D | Group E | P | Group A | Group B | Group C | Group D | Group E | P | |
Cycles (n) | 1425 | 844 | 206 | 183 | 120 | 144 | 269 | 107 | 39 | 25 | ||
Preterm birth (<37weeks) | 11.77a,b,c (91/773) | 39.45 (215/545) | 33.33 (44/132) | 42.70 (38/89) | 4.55d (2/44) | 0.000 | 8.20a,b (5/61) | 35.0 (56/160) | 25.0 (13/52) | 16.67 (2/12) | 16.67 (1/6) | 0.001 |
Singleton | 8.67a (67/773) | 3.30 (18/545) | 6.82 (9/132) | 3.37 (3/89) | 4.55 (2/44) | 0.001 | 4.92 (3/61) | 5.62 (9/160) | 7.69 (4/52) | 0.0 (0/12) | 0.0 (0/6) | 0.755 |
Twin | 3.10a,b,c (24/773) | 36.15 (197/545) | 26.51 (35/132) | 39.33 (35/89) | 0.0d (0/44) | 0.000 | 3.28a,b (2/61) | 29.38 (47/160) | 17.31 (9/52) | 16.67 (2/12) | 16.67 (1/6) | 0.000 |
Gestational age (weeks) | 38.70 ± 1.94a,b,c | 37.37 ± 2.52 | 37.59 ± 2.52 | 36.86 ± 3.33 | 39.18 ± 1.91d | 0.000 | 38.72 ± 1.23a,b,c | 37.61 ± 2.33 | 37.66 ± 2.89 | 37.00 ± 3.43 | 38.32 ± 0.86d | 0.022 |
Singleton | 38.80 ± 1.83 | 38.94 ± 1.71 | 38.51 ± 2.18 | 39.00 ± 1.58 | 39.18 ± 1.91 | 0.325 | 38.81 ± 1.56 | 38.59 ± 2.14 | 38.76 ± 1.97 | 38.52 ± 1.71 | 38.32 ± 0.86 | 0.951 |
Twin | 35.32 ± 1.47 | 36.04 ± 2.32 | 36.02 ± 2.37 | 35.15 ± 3.01 | / | 0.095# | 36.20 ± 0.40 | 35.98 ± 1.63 | 35.06 ± 3.21 | 34.29 ± 4.99 | / | 0.330# |
Birth height (mm) | 49.51 ± 2.3a,b,c | 47.72 ± 3.21 | 48.23 ± 2.41 | 46.61 ± 4.26 | 49.89 ± 2.22d | 0.000 | 49.77 ± 1.85a,b,c | 48.03 ± 2.70 | 47.95 ± 3.75 | 48.31 ± 5.70 | 49.75 ± 0.96d | 0.000 |
Singleton | 49.68 ± 2.27 | 49.82 ± 1.98 | 49.88 ± 1.73 | 49.53 ± 1.44 | 49.88 ± 2.22 | 0.838 | 49.93 ± 1.76 | 49.50 ± 2.39 | 49.77 ± 2.41 | 50.00 ± 2.00 | 49.75 ± 0.96 | 0.868 |
Twin | 46.66 ± 2.40 | 46.72 ± 2.95 | 46.97 ± 2.20 | 45.50 ± 4.32 | / | 0.113# | 46.75 ± 0.35 | 46.90 ± 1.91 | 45.70 ± 3.70 | 45.83 ± 6.83 | / | 0.155# |
Birth weight (kg) | 3.16 ± .054a,b,c | 2.73 ± 0.61 | 2.79 ± 0.62 | 2.57 ± 0.66 | 3.19 ± 0.43d | 0.000 | 3.12 ± 0.51a,b,c | 2.76 ± 0.60 | 2.81 ± 0.75 | 2.55 ± 0.88 | 3.30 ± 0.29d | 0.000 |
Singleton | 3.22 ± 0.50 | 3.27 ± 0.51 | 3.24 ± 0.52 | 3.17 ± 0.33 | 3.19 ± 0.43 | 0.583 | 3.36 ± 0.49 | 3.22 ± 0.50 | 3.24 ± 0.49 | 3.26 ± 0.45 | 3.30 ± 0.29 | 0.666 |
Twin | 2.34 ± 0.43 | 2.48 ± 0.45 | 2.44 ± 0.42 | 2.31 ± 0.54 | / | 0.113# | 2.55 ± 0.25 | 2.43 ± 0.34 | 2.24 ± 0.52 | 2.00 ± 0.82 | / | 0.142# |
Still birth | 0.0 (0/773) | 0.0 (0/545) | 0.0 (0/132) | 0.0 (0/89) | 0.0 (0/44) | / | 0.0 (0/61) | 0.0 (0/160) | 0.0 (0/52) | 0.0 (0/12) | 0.0 (0/6) | / |
Congenital anomalies | 1.64 (13/795) | 1.60 (13/811) | 1.09 (2/184) | 1.52 (2/132) | 2.27 (1/44) | 0.958 | 0.0 (0/63) | 0.0 (0/217) | 0.0 (0/68) | 0.0 (0/15) | 0.0 (0/6) | / |
Sex ratio(male/female) | 1.30 (450/345) | 1.43 (477/334) | 1.10 (97/87) | 1.46 (78/54) | 0.83 (20/24) | 0.445 | 1.43 (37/26) | 1.22 (119/98) | 1.16 (37/31) | 0.63 (6/9) | 1.00 (3/3) | 0.632 |
Low birth weight (<2500 g) in singleton | 7.04a,b,c (56/795) | 27.25 (221/811) | 28.26 (52/184) | 34.09 (45/132) | 4.55d (2/44) | 0.000 | 6.34a,b (4/63) | 29.03 (63/217) | 27.94 (19/68) | 13.33 (2/15) | 0.0 (0/6) | 0.002 |
Singleton | 4.02 (32/795) | 4.44 (36/811) | 4.35 (8/184) | 4.55 (6/132) | 4.55 (2/44) | 0.977 | 3.17 (2/63) | 2.76 (6/217) | 1.47 (1/68) | 0.0 (0/1) | 0.0 (0/6) | 0.833 |
Twin | 3.02a,b,c (24/795) | 22.81 (185/811) | 23.91 (44/184) | 29.54 (39/132) | 0.0d (0/44) | 0.000 | 3.17a,b (2/63) | 26.27 (57/217) | 26.47 (18/68) | 13.33 (2/15) | 0.0 (0/6) | 0.001 |
Very low birth weight (<1500 g) in singleton | 0.75a,c (6/795) | 2.84 (23/811) | 1.63 (3/184) | 5.30 (7/132) | 0.0 (0/44) | 0.001 | 0.0c (0/63) | 2.76 (6/217) | 2.94 (2/68) | 13.33 (2/15) | 0.0 (0/6) | 0.045 |
Singleton | 0.63 (5/795) | 0.12 (1/811) | 0.54 (1/184) | 0.0 (0/132) | 0.0 (0/44) | 0.324 | 0.0 (0/63) | 0.5 (1/217) | 0.0 (0/68) | 0.0 (0/15) | 0.0 (0/6) | 0.879 |
Twin | 0.12a,c (1/795) | 2.72 (22/811) | 1.09 (2/184) | 5.30 (7/13) | 0.0 (0/44) | 0.000 | 0.0c (0/63) | 2.30 (5/217) | 2.94 (2/68) | 13.33 (2/15) | 0.0 (0/6) | 0.029 |