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Table 3 Descriptive statistical analysis of basic information of eight patients

From: Whole-exome sequencing reveals ANO8 as a genetic risk factor for intrahepatic cholestasis of pregnancy

ICP

SNP

Additional variantsa

Age (years)

Gestational age (weeks)

BMI (kg/m2)

TBA (µmol/L)

Gravidity (times)

Parity (times)

Type of delivery

ICP66

rs1316267732

No

30

38 + 1

24.8

129.3

3

1

Cesarean

ICP64b

rs1

No

26

33 + 6

33.3

47.6

1

0

Cesarean

ICP40

rs2

No

33

35 + 1

22.1

185.5

3

1

Cesarean

ICP158

rs3

No

30

38 + 3

21.0

37.5

3

0

Cesarean

ICP50

rs760834212

No

23

35 + 6

26.4

120.8

2

0

Cesarean

ICP28

rs1391524054

No

24

40 + 1

22.8

14.8

1

0

Vaginal delivery

ICP151

rs4

No

31

31 + 3

27.4

78.2

2

1

Spontaneous abortion

ICP148

rs5

No

31

17

25.1

133.2

3

1

Spontaneous abortion

  1. a The patient did not contain any possible pathogenic mutations in the ABCB4, ABCB11, ATP8B1 and TJP2 genes
  2. b The new SNPs are marked with a gray background