Skip to main content

Table 4 Frequency distribution of estimated parasite densities of P .falciparum infections detected by each diagnostic test

From: Evaluation of highly sensitive diagnostic tools for the detection of P. falciparum in pregnant women attending antenatal care visits in Colombia

Diagnostic test

n

No. of infections detected by parasite density category (% of qRT-PCR-positive) a

<  1 p/μL

1–10 p/μL

10–100 p/μL

> 100 p/μL

(n = 12)

(n = 3)

(n = 9)

(n = 14)

Microscopy

22

0 (0)

0 (0)

8 (88.9)

14 (100)

cRDT

20

0 (0)

0 (0)

6 (66.7)

14 (100)

hsRDT

24

1 (8.3)

0 (0)

9 (100)

14(100)

LAMP

34

9 (75.0)

2 (66.7)

9 (100)

14 (100)

nPCR

29

5 (41.7)

1 (33.3)

9 (100)

14 (100)

  1. aRefers to P. falciparum mono-infections (i.e., mixed infection not included. p/μL: estimated parasites per microliter, qRT-PCR Quantitative Reverse Transcription polymerase chain reaction, cRDT conventional rapid diagnostic test, hsRDT highly sensitive rapid diagnostic test, nPCR nested polymerase chain reaction, LAMP loop-mediated isothermal amplification