BMC Pregnancy and Childbirth

Table 1 Sensitivity, Specificity, and AUC of each biomarker under Bayesian latent class model assuming without a gold standard

From: Diagnostic accuracy of maternal serum multiple marker screening for early detection of gestational diabetes mellitus in the absence of a gold standard test

Biomarker	Parameters	Mean	Median	SD	MC error	95% CrI^a
uE3
	Sensitivity	0.67	0.66	0.15	0.02	0.58–0.72
	Specificity	0.86	0.88	0.002	0.0007	0.81–0.88
	AUC	0.65	0.65	0.12	0.01	0.56–0.69
β-hCG
	Sensitivity	0.78	0.77	0.20	0.03	0.70–0.84
	Specificity	0.82	0.82	0.003	0.0007	0.79–0.85
	AUC	0.62	0.62	0.18	0.04	0.54–0.68
AFP
	Sensitivity	0.71	0.70	0.06	0.002	0.66–0.78
	Specificity	0.92	0.93	0.06	0.002	0.89–0.98
	AUC	0.58	0.58	0.07	0.002	0.51–0.62

uE3 unconjugated estriol, β-hCG beta-human chorionic gonadotropin, AFP alfa-Fetoprotein, SD standard deviation, MC monte carlo, CrI credible interval, AUC area under receiver operating characteristic curve

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ISSN: 1471-2393

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