Fig. 1

Antidiabetic drug use, by trimester, in the cohort of pregnancies among women with pre-existing diabetes during 2001–2013 in the MSDD. † 90 days prior is the period of 90 days prior to the calculated start of pregnancy based on the pregnancy period algorithm using livebirth delivery claim codes. 1st Tri, 2nd Tri, and 3rd Tri refer to the gestational trimesters, also calculated using the pregnancy period algorithm based on delivery codes. Individual pregnancies could be counted in multiple gestational terms and for multiple drug categories. ‡Other category includes alpha-glucosidase inhibitors, meglitinide analogs, amylin analog, DPP-4 inhibitors, GLP-1 receptor agonists, thiazolidinediones, and combination products