Table 1 Unadjusted values for vascular measures and biomarkers by trimester and postpartum
Measure | 1st trimester n = 17 | 2nd trimester n = 32 | 3rd trimester n = 37 | 1st postpartum n = 35 | 2nd postpartum n = 14 | Overall P-value |
|---|---|---|---|---|---|---|
Inter-adventitial diameter (mm) | 6.47 (0.12) | 6.79 (0.08) | 6.89 (0.10) | 6.36 (0.07) | 6.42 (0.11) | <  0.0001 |
CCA intima-media thickness (mm) | 0.547 (0.02) | 0.546 (0.01) | 0.553 (0.01) | 0.565 (0.01) | 0.581 (0.02) | 0.03 |
Weight (kg) | 68.7 (2.2) | 73.1 (1.6) | 79.5 (1.8) | 69.2 (1.5) | 70.2 (1.9) | <  0.0001 |
Weight change (kg) | 0.55 (0.46) | 7.27 (0.62) | 14.4 (0.91) | 4.3 (0.75) | 3.7 (1.1) | <  0.0001 |
Systolic blood pressure (mm Hg) | 103.7 (2.1) | 106.0 (1.7) | 110.4 (1.4) | 106.2 (1.7) | 102.9 (2.5) | <  0.0001 |
Heart rate (bpm) | 78.0 (2.4) | 79.8 (1.6) | 82.0 (1.5) | 68.1 (1.5) | 63.6 (2.5) | <  0.0001 |
Total cholesterol (mg/dl) | 201.7 (8.9) | 257.3 (7.0) | 273.1 (7.2) | 191.4 (5.5) | 194.8 (8.4) | <  0.0001 |
LDL-c (mg/dl) | 111.2 (7.0) | 148.0 (6.3) | 155.5 (6.6) | 114.7 (4.8) | 121.9 (7.0) | <  0.0001 |
Triglycerides (mg/dl) | 108.3 (10.5) | 176.5 (10.2) | 250.7 (13.6) | 77.3 (7.0) | 87.1 (9.6) | <  0.0001 |
HDL-c (mg/dl) | 68.8 (2.2) | 74.0 (3.1) | 66.8 (2.3) | 61.2 (1.8) | 55.6 (2.9) | <  0.0001 |
Glucose (mg/dl) | 79.3 (1.5) | 77.2 (1.1) | 77.0 (1.2) | 82.6 (1.2) | 88.5 (1.9) | <  0.0001 |
Insulin (μU/ml) | 8.84 (0.78) | 11.25 (0.98) | 11.95 (0.81) | 8.59 (0.50) | 10.76 (0.82) | 0.0008 |
HOMA-IR | 1.64 [1.32, 2.09] | 2.16 [1.56, 2.56] | 2.28 [1.67, 2.51] | 1.72 [1.34, 2.13] | 2.20 [1.76, 2.87] | 0.03 |
hsCRP (mg/L) | 3.58 [2.16, 5.57] | 3.36 [2.31, 5.49] | 3.29 [2.24, 7.01] | 1.20 [.77, 2.44] | 0.96 [0.37, 1.50] | <  0.0001 |