Do pregnancies reduce iron overload in HFE hemochromatosis women? results from an observational prospective study

Table 3 Biological parameters of the p.Cys282Tyr homozygous hemochromatosis women according to the number of pregnancies that women had prior to entry into the phlebotomy program

Biological parameters	Number of pregnancies: 0		Number of pregnancies: 1 or 2		Number of pregnancies: ≥ 3		P‡
Biological parameters	Median	IQR^a	Median	IQR	Median	IQR
Transferrin saturation (%) (n = 137)
	81	[72–89]	78	[65–88]	83	[67–97]	0.998
Serum ferritin (μg/L) (n = 137)
	298	[236–529]	414	[279–693]	412	[297–770]	0.293
Amount of iron removed (g) (n = 127)
	1.3	[1.1–2.0]	2.5	1.4–4.0]	2.3	[1.6–3.6]	0.140
Hemoglobin (g/dL) (n = 108)
	13.6	[13.3–14.6]	14.0	[13.6–14.5]	13.9	[13.4–14.4]	0.815

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