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Table 1 Prevalence of congenital hydrocephalus (1/10,000) in China during 2005–2012, stratified by maternal age, residential area, gender, and plurality of pregnancy

From: Changes in prevalence and perinatal outcomes of congenital hydrocephalus among Chinese newborns: a retrospective analysis based on the hospital-based birth defects surveillance system

 

Number of Births

Isolated CH (N = 5245)

Associated CH (N = 1245)

Total CH (N = 6490)

Number

Prevalence

(95%CI)

PR

(95%CI)

Number

Prevalence (95%CI)

PR

(95%CI)

Number

Prevalence (95%CI)

PR

(95%CI)

Maternal age (years)a

  < 20

196,160

155

7.90 (6.66–9.15)

1.88 (1.60–2.22)

29

1.48 (0.94–2.02)

1.50 (1.03–2.18)

184

9.38 (8.02–10.74)

1.81 (1.56–2.10)

 20–24

2,764,522

1677

6.07 (5.78–6.36)

1.45 (1.35–1.54)

314

1.14 (1.01–1.26)

1.15 (1.00–1.33)

1991

7.20 (6.89–7.52)

1.39 (1.31–1.48)

 25–29

4,435,764

1863

4.20 (4.01–4.39)

1.00 (ref)

438

0.99 (0.89–1.08)

1.00 (ref)

2301

5.19 (4.98–5.40)

1.00 (ref)

 30–34

2,233,043

1008

4.51 (4.24–4.79)

1.08 (1.00–1.16)

279

1.25 (1.10–1.40)

1.27 (1.09–1.47)

1287

5.76 (5.45–6.08)

1.11 (1.04–1.19)

 ≥35

944,572

540

5.72 (5.23–6.20)

1.36 (1.24–1.50)

185

1.96 (1.68–2.24)

1.98 (1.67–2.36)

725

7.68 (7.12–8.23)

1.48 (1.36–1.61)

Residential areab

 Urban

5,630,037

2323

4.13 (3.96–4.29)

1.00 (ref)

582

1.03 (0.95–1.12)

1.00 (ref)

2905

5.16 (4.97–5.35)

1.00 (ref)

 Rural

4,944,024

2920

5.91 (5.69–6.12)

1.43 (1.36–1.51)

662

1.34 (1.24–1.44)

1.30 (1.16–1.45)

3582

7.25 (7.01–7.48)

1.40 (1.34–1.48)

Genderc

 Female

4,940,848

2323

4.70 (4.51–4.89)

1.00 (ref)

513

1.04 (0.95–1.13)

1.00 (ref)

2836

5.74 (5.53–5.95)

1.00 (ref)

 Male

5,630,497

2906

5.16 (4.97–5.35)

1.10 (1.04–1.16)

703

1.25 (1.16–1.34)

1.20 (1.07–1.35)

3609

6.41 (6.20–6.62)

1.12 (1.06–1.17)

Plurality of pregnancyd

 Singleton

10,412,509

5051

4.85 (4.72–4.98)

1.00 (ref)

1190

1.14 (1.08–1.21)

1.00 (ref)

6241

5.99 (5.85–6.14)

1.00 (ref)

 Multiple

161,552

192

11.88 (10.20–13.57)

2.45 (2.12–2.83)

55

3.40 (2.50–4.30)

2.98 (2.27–3.91)

247

15.29 (13.38–17.20)

2.55 (2.25–2.90)

  1. Abbreviations: CI Confidence interval, PR Prevalence ratio, Ref Reference
  2. a2 cases with unspecified maternal age were excluded; b3 cases with unspecified residential area were excluded; c40 cases with unknown gender and 5 cases with unspecified gender were excluded; d2 cases with unspecified plurality of pregnancy were excluded
  3. Values in bold represent statistical significance at a 95% confidence level