Table 1 Maternal characteristics at baseline (n = 23)
Intervention (Glibenclamide)(n = 13) | Standard (Insulin) (n = 10) | Total (n = 23) | |||||
|---|---|---|---|---|---|---|---|
Maternal age (years) | Mean (SD) | 33.0 (5.1) | 34.5 (4.9) | 33.7 (5.0) | |||
BMI (kg/m2) at randomisation | |||||||
< 40 | n (%) | 8 (61.5) | 8 (80.0) | 16 (69.6) | |||
≥ 40 | n (%) | 5 (38.5) | 2 (20.0) | 7 (30.4) | |||
Median [IQR] | 39.2 [33.2 to 40.6] | 33.3 [29.5 to 38.2] | 35.7 [32.0 to 40.5] | ||||
Gestational age at randomisation (weeks) | Mean (SD) | 29.6 (6.3) | 31.5 (2.2) | 30.4 (4.9) | |||
Gestation at diagnosis of gestational diabetes (weeks) | Median [IQR] | 24.9 [17.6 to 28.9] | 27.1[24.0 to 28.9] | 26.7[17.6 to 28.9] | |||
Daily dose of metformin at randomisation (mg) | Median [IQR] | 1500 [1500 to 2000] | 1500 [1500 to 2000] | 1500 [1500 to 2000] | |||
Ethnicity | |||||||
White | n (%) | 10 | (76.9) | 7 | (70.0) | 17 | (73.9) |
Indian | n (%) | 0 | (0.0) | 2 | (20.0) | 2 | (8.7) |
Pakistani | n (%) | 1 | (7.7) | 1 | (10.0) | 2 | (8.7) |
Bangladeshi | n (%) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) |
Other Asian background | n (%) | 1 | (7.7) | 0 | (0.0) | 1 | (4.4) |
Black | n (%) | 1 | (7.7) | 0 | (0.0) | 1 | (4.4) |
Deprivation levela | |||||||
1 (Most deprived) | n (%) | 6 | (46.2) | 4 | (40.0) | 10 | (43.5) |
2 | n (%) | 3 | (23.1) | 2 | (20.0) | 5 | (21.7) |
3 | n (%) | 1 | (7.7) | 0 | (0.0) | 1 | (4.3) |
4 | n (%) | 2 | (15.4) | 1 | (10.0) | 3 | (13.0) |
5 (Least deprived) | n (%) | 1 | (7.7) | 3 | (30.0) | 4 | (17.4) |
Number of previous pregnanciesb | |||||||
0 | n (%) | 1 | (7.7) | 2 | (22.2) | 3 | (13.6) |
1 or more | n (%) | 12 | (92.3) | 7 | (77.8) | 19 | (86.4) |
Blood pressure (mmHg) | |||||||
Systolic | Mean (SD) | 118.4 | (11.4) | 122.2 | (10.8) | 120.0 | (11.0) |
Diastolic | Mean (SD) | 72.2 | (7.0) | 72.6 | (8.7) | 72.3 | (7.6) |