Table 2 First prenatal test, time of diagnosis and pregnancy outcome according to year of birth in cases with a common trisomy (T21, T18, T13) in women < =35 years and >35 years
Year of birth | ||||||
|---|---|---|---|---|---|---|
2005–2006 | 2007–2012 | Total | ||||
Women < = 35 years | N = 61 | N = 169 | N = 230 | |||
First prenatal test** | ||||||
PNS1 | 15 | 25% | 42 | 25% | 57 | 25% |
PNS2 | 1 | 2% | 76 | 45% | 77 | 33% |
PND | 12 | 20% | 9 | 5% | 21 | 9% |
No PNS or PND | 33 | 54% | 42 | 25% | 75 | 33% |
Time of diagnosis** | ||||||
Postnatal | 34 | 56% | 89 | 53% | 123 | 53% |
Prenatal < 24 weeks | 18 | 30% | 73 | 43% | 91 | 40% |
Prenatal > = 24 weeks | 9 | 15% | 7 | 4% | 16 | 7% |
Pregnancy outcome | ||||||
Live birth | 34 | 56% | 94 | 56% | 128 | 56% |
Fetal death | 8 | 13% | 17 | 10% | 25 | 11% |
TOP | 19 | 31% | 58 | 34% | 77 | 33% |
Women >35 years* | N = 67 | N = 199 | N = 266 | |||
First prenatal test** | ||||||
PNS1 | 32 | 48% | 116 | 58% | 148 | 56% |
PNS2 | 3 | 4% | 33 | 17% | 36 | 14% |
PND | 17 | 25% | 28 | 14% | 45 | 17% |
No PNS or PND | 15 | 22% | 22 | 11% | 37 | 14% |
Time of diagnosis | ||||||
Postnatal | 18 | 27% | 54 | 27% | 72 | 27% |
Prenatal < 24 weeks | 46 | 69% | 139 | 70% | 185 | 70% |
Prenatal > = 24 weeks | 3 | 4% | 6 | 3% | 9 | 3% |
Pregnancy outcome | ||||||
Live birth | 21 | 31% | 54 | 27% | 75 | 28% |
Fetal death | 6 | 9% | 22 | 11% | 28 | 11% |
TOP | 40 | 60% | 123 | 62% | 163 | 61% |