Figure 2
Spatial and temporal expression of splicing factors in the myometrium during pregnancy. (A) SF2/ASF, hnRNPA1, SRp40, SC35, PSF and UI-A snRNP protein expression within the upper and lower uterine regions of the human myometrium. Data are shown as the mean (n = 10) for non-pregnant (NP), term not in labour; upper (PU) and lower uterine regions and labouring upper (LU) and lower uterine regions (LL). (B) The switch in the expression of SF2/ASF, hnRNPA1, SRp40, SC35, PSF and UI-A snRNP within the upper and lower uterine regions from the non-pregnant to the term pregnant is indicated (red). Differential expression profiles for spliced variants of the transcriptional factors CREMτ2α, CREMα and ATF-2 are also shown (black).