Figure 2

Representative LRR and BAF plots for a genomic region called and assay confirmed as a deletion. LRR and BAF values for each probe are represented as dots. The vertical grey bars delineate the boundaries of the algorithm-detected deletion (chr13:83.004-83.045 Mb). LRR values for the SNP and copy-number probes in the deletion (red dots) drop to the -0.5 region and BAF values for the SNP probes cluster randomly around 0 or 1. In comparison, the flanking normal chromosomal regions have LRR values centered around zero with three BAF clusters (blue dots).