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Table 5 Development of the prediction model for LGA risk

From: A first trimester prediction model for large for gestational age infants: a preliminary study

 

Univariate analyses

(n = 503)

Multivariable prediction model

(n = 434)

 

OR

95% CI

p

OR

95% CI

p

Maternal Age (+ 1 year)

1.03

0.98

1.08

0.283

    

Multiparity

2.41

1.51

3.86

0.001

2.80

1.61

4.87

0.001

Italian place of origin

1.17

0.61

2.45

0.065

    

Pre-pregnancy BMI (+ 1 kg/m2)

1.08

1.04

1.12

0.001

1.08

1.03

1.14

0.002

Pre-existing diabetes

5.04

1.00

25.38

0.050

    

HDL ≥ 50 mg/dL

0.63

0.30

1.29

0.206

    

TG ≥ 150 mg/dL

1.76

0.96

3.23

0.068

    

Insulin ≥ 24 (+ 1μUI/mL)

1.74

0.92

3.29

0.091

    

PAPP-A (+ 1 MoM)

1.30

1.00

1.70

0.051

1.43

1.08

1.90

0.013

PlGF (+ 1 MoM)

1.21

0.75

1.97

0.432

    

IL-6 (+ 1 pg/mL)

1.00

1.00

1.00

0.477

    

Inhibin A (+ 1 pg/mL)

1.00

1.00

1.00

0.338

    

FCF ≥ 162

0.69

0.41

1.16

0.157

    

Metabolic Syndrome

1.70

0.70

4.12

0.244

    
  1. The variables that were associated to LGA risk with p-value < 0.10 in the univariate analyses were considered for inclusion in a multivariable logistic model. The final prediction model was determined by a stepwise backward selection procedure in which only independent variables associated to LGA risk with p-value < 0.05 were retained