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Table 3 Logistic regression to predict the poor neonatal outcomes including brain image anomaly, PROM within 3 weeks after laser operation, and delivery before the gestational age of 28 weeks in TTTS postlaser therapy

From: Effects and outcomes of septostomy in twin-to-twin transfusion syndrome after fetoscopic laser therapy

Observed poor outcomes

Variable 1(septostomy)

Variable 2 (severe Quintero stage)

Neonatal cerebral image anomaly

(p = 0.03, Odds ratio = 5.1 (1.18–22.2))

Not significant

PROMs within three weeks after laser operation

(p = 0.001,Odds ratio = 14.1 (2.8–70.1))

(p = 0.03, Odds ratio = 5.4 (1.2–25.0))

Delivery before gestational age of 28 weeks

(p = 0.017, Odds ratio = 4.5 (1.3–15.8))

(p = 0.034, Odds ratio = 2.3 (1.1–5.1))

  1. The odds ratios of the variables were expressed as odds ratio (95% confidence interval)
  2. Severe Quintero stages included Quintero stage III and stage IV
  3. PROMs Premature rupture of membranes
  4. TTTS Twin-to-twin transfusion syndrome