The change in haemoglobin concentration between the first and third trimesters of pregnancy: a population study

Churchill, David; Nair, Manisha; Stanworth, Simon J.; Knight, Marian

doi:10.1186/s12884-019-2495-0

BMC Pregnancy and Childbirth

Table 2 Total population changes in haemoglobin concentration between the first and 3rd trimesters and stratified sub-groups by ethnicity, deprivation and body size as represented by the body mass index (BMI). ΔHB(%) – represents the absolute change in haemoglobin and the percentage change in brackets

From: The change in haemoglobin concentration between the first and third trimesters of pregnancy: a population study

	1st Trimester Hb					3rd Trimester Hb
Sample	N	mean	SD	IQ	5/95%	N	mean	SD	IQ	5/95%	ΔHB(%)
Total Population	7054	127.9	11.2	121–134	108/143	6642	113.7	10.3	107–121	96/130	−14.2(11)
South Asians ^a	1097	123.4	10.9	117–130	104/140	1042	110.8	11.13	104–119	93/128	−12.6(10.2)
Blacks ^a	294	121.5	11.4	115–129	102/139	274	109.6	9.77	104–116	93/125	−11.9(9.8)
Mixed^a	76	127.8	8.53	122–133	113/142	74	111.0	8.48	105–118	97/125	−16.8(13.4)
White ^a	4405	129	10.6	123–136	112/144	4191	114.9	9.81	109–121	98/131	−14.1(10.9)
Subgroup H ^b	5663	128	10.3	122–135	111/144	5298	114	9.8	108–121	98/130	−14(10.9)
Subgroup I ^c	728	117	12.7	109–126	95/136	676	108	12.1	100–116	88/128	−9(7.7)
IMD Q1 (most deprived)	3957	126	11.3	120–134	107/143	3720	112.8	10.5	106–120	95/129	−9(7.7)
IMD Q2	1074	126.9	11.7	122–134	107/143	1011	113.7	10.2	108–120	96/130	−13.2(10.4)
IMD Q3	778	128	10.1	122–135	110/144	739	115	9.8	109–121	99/131	−13(10.1)
IMD Q4	741	128	10.7	122–135	111/144	695	115.5	9.7	109–122	99/131	−12.5(9.8)
IMD Q5 (least deprived)	455	128.5	10.5	123–135	114/144	438	115.7	9.2	110–121	101/131	−12.8((9.3)
IMD Q1 ^a	1037	128.9	9.06	123–135	114/144	1008	113.8	9.79	108–121	97/129	−15.1(11.7)
IMD Q2&3 ^a	4273	126.6	11.27	120–134	107/143	4025	112.9	10.49	106–120	95/129	−13.7(10.8)
IMD Q 4&5 ^a	918	128.6	10.4	123–135	111/144	871	115.6	9.49	109–122	100/131	−13(10.1)
BMI Obese	1711	128.8	10.8	123–136	110/145	1604	115.8	9.8	110–122	99/132	−13(16.7)
BMI Underweight	231	124.5	10.9	117–132	107/141	222	110.5	11.5	104–117	89/128	−14(17.3)
BMI normal+overweight	4946	126.5	11.2	121–134	107/143	4678	113.1	10.3	107–120	96/129	−13.4(16.9)
IMD1 excluding obese	2832	125.8	11.4	120–133	106/142	2679	111.9	10.6	105–119	94/129	−13.9 (17.4)

Each subgroup represents the total population excluding the women as shown by the symbols below
^a Restricting the sample to pregnant women without the following problems during index pregnancy current pregnancy problems, pregnancy induced hypertension, Pre-term birth, antepartum haemorrhage, pre-pregnancy med problems, diabetes, hypertension, renal disease, & anaemia in 1st trimester
^b women without a haemoglobinopathy trait
^c Women with an haemoglobinopathy trait
IMD = Index of multiple deprivation

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ISSN: 1471-2393

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