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Table 2 Characteristics of pregnant women with incident or prevalent depression during pregnancy or up to 6 months after the end of pregnancy of pregnancy who did and did not develop treatment resistant depression

From: Treatment resistant depression in women with peripartum depression

Characteristic

Pregnant women with depression but not TRD

(n = 74,835)

Pregnant women with TRD

(n = 4354)

P value

Age, years (mean, sd)

31.0

6.1

30.5

6.3

< 0.0001

Age group, years (n, %

 12–24

11,383

15.2%

780

17.9%

< 0.0001

 25–34

42,113

56.3%

2387

54.8%

 35–44

20,647

27.6%

1141

26.2%

 45–56

692

0.9%

46

1.1%

Deyo-Charlson severity index (mean, sd)

0.33

1.01

0.38

1.02

0.002

Comorbidities in prior year (n, %)

 Fatigue

527

0.7%

40

0.9%

0.115

 Opioid dependence

427

0.6%

67

1.5%

< 0.0001

 Drug abuse

371

0.5%

40

0.9%

< 0.0001

 Tobacco dependence syndrome

2460

3.3%

200

4.6%

< 0.0001

 Anxiety disorder

17,630

23.6%

1483

34.1%

< 0.0001

 Obsessive-compulsive disorder

672

0.9%

87

2.0%

< 0.0001

 Social phobia

127

0.2%

10

0.2%

0.345

 Eating disorder

471

0.6%

42

1.0%

0.011

 Insomnia

2192

2.9%

294

6.8%

< 0.0001

 Pain of head and neck

14,504

19.4%

1107

25.4%

< 0.0001

 Musculoskeletal pain

9354

12.5%

660

15.2%

< 0.0001