Fig. 4
From: The importance of the PD-1/PD-L1 pathway at the maternal-fetal interface
Cytotoxicity of PD-1 positive/negative immune cell populations in 1st-trimester healthy pregnant and in non-pregnant women. Box plot of the median, the 25th and, 75th percentiles, range, and individual data values for the expression of the CD107a molecule by PD-1+/PD-1 negative immune cells (a and b) and PD-1+/PD-1 negative CD8+ T cells (c and d) in peripheral blood and decidual tissue in healthy pregnant and in non-pregnant women. The middle line within the box represent medians of 10, 13 and 7 determinations, respectively, the middle dot within the box represents the mean, the boxes indicate the interquartile ranges and the whiskers show the most extreme observations. Differences were considered statistically significant for p-values ≤ 0.05. ***p < 0,01; **p < 0,03