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Table 2 Analysis Results of NBL, PNT and IOD According to Gestational Weeks

From: Reference ranges for foetal nasal bone length, prenasal thickness, and interocular distance at 18 to 24 weeks’ gestation in low-risk pregnancies

Variable

Gestational Age (weeks)

p

18

19

20

21

22

23

24

NBL

5.53 ± 0.73a

5.83 ± 0.66a

6.53 ± 0.74b

6.79 ± 0.76b

7.29 ± 0.94c

7.63 ± 0.79c

8.33 ± 1.02d

p < 0.001*

PNT

3.52 ± 0.70a

3.63 ± 0.82ab

4.03 ± 0.56bc

4.38 ± 0.69cd

4.63 ± 0.77de

4.48 ± 0.75d

5.06 ± 0.97e

p < 0.001*

IOD

11.15 ± 1.36a

11.55 ± 1.25a

12.30 ± 1.31b

12.79 ± 1.29b

13.49 ± 1.17c

13.64 ± 1.09c

14.54 ± 1.48d

p < 0.001*

PNT/NBL

0.63 ± 0.11

0.62 ± 0.14

0.62 ± 0.10

0.65 ± 0.11

0.64 ± 0.11

0.59 ± 0.11

0.61 ± 0.11

0.141

  1. a,b,c,d,eindicate differences for each group. *indicates statistical significance between gestational weeks and the variable. p < 0.05 for the differences between subgroups. Values are expressed as the mean ± SD
  2. NBL Nasal bone length, PNT Prenasal thickness, IOD Interocular distance