Organism | Study | Number of infants (n) in each group | Log colony forming units per gram (CFU/g) | |||
---|---|---|---|---|---|---|
Day 3 | Day 6/7 | Day 30 | Day 90 | |||
Family | ||||||
Staphylococcaceae | Arboleya 2015 [32] | IAP n = 14 Control n = 13 |  |  | Lower log cells/g in IAP, p < 0.05 |  |
Enterobacteriaceae | Arboleya 2015 [32] | IAP n = 14 Control n = 13 |  |  | Higher log cells/g in IAP, p < 0.05 |  |
Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 8.4 (R 3.3-9.5) Control: Md 9.2 (R 3.3-9.8) p = 0.18 |  |  |  | |
Genera | ||||||
Bacteroides | Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 8.0 (R 6.3-10.3) Control: Md 7.9 (R 3.6-9.6) p = 0.12 |  |  |  |
Bifidobacteria | Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 8.2 (R 4.3-9.5) Control: Md 8.5 (R 6.9-10.3) p = 0.10 |  |  |  |
Arboleya 2015 [32] | IAP n = 14 Control n = 13 |  |  |  | Lower log cells/g in IAP, p < 0.05 | |
Bifidobacterium spp. | Aloisio 2014 [30]a | IAP n = 26 Control n = 26 |  | IAP: M 5.85 (R 3.24-7.79) Control: M 7.29 (R 4.12-10.95) p = 0.001 |  |  |
Corvaglia 2016 [36]a | IAP n = 35 Control n = 29 |  | IAP: Md 6.01 (IQR 5.51-6.98) Control: Md 7.80 (IQR 6.61-8.26) p = 0.000 | IAP: Md 8.41 (IQR 7.71-8.80) Control: Md 8.39 (IQR 7.96-8.86) p = 0.363 |  | |
Mazzola 2016 [57]a | Breast-fed IAP n = 7 Breast-fed Control n = 7 |  | IAP: Md 5.86 Control: Md 8.16 p = 0.005 | IAP: Md 7.72 (compared to day 7, p = 0.035) Control: Md 8.62 NS |  | |
Mixed-fed IAP n = 6 Mixed-fed Control n = 6 |  | IAP: Md 5.81 Control: Md 7.19 p = 0.03 | IAP: Md 8.50 (compared to day 7, p = 0.036) Control Md 8.55 (compared to day 7, p = 0.028) |  | ||
Clostridia | Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 5.3 (R 4.3-5.8) Control: Md 6.2 (R 3.6-8.1) p = 0.01 |  |  |  |
Enterococci | Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 8.3 (R 3.6-10.3) Control: Md 7.3 (R 3.3-9.5) p = 0.78 |  |  |  |
Lactobacillus spp. | Aloisio 2014 [30]a | IAP n = 26 Control n = 26 |  | IAP: M 6.69 (R 5.40-8.93) Control: M 6.73 (R 5.45-8.20) NS |  |  |
Corvaglia 2016 [36]a | IAP n = 35 Control n = 29 |  | IAP: Md 5.56 (IQR 4.94-6.14) Control: Md 5.45 (IQR 4.81-6.14) p = 0.872 | IAP: Md 5.29 (IQR 4.68–6.01) Control: Md 5.25 (IQR 4.60-6.15) p = 0.932 |  | |
Staphylococci | Jaureguy 2004 [39]a | IAP n = 25 Control n = 25 | IAP: Md 6.5 (R 3.6-8.0) Control: Md 7.0 (R 4.0-9.3) p = 0.53 |  |  |  |
Species | ||||||
Escherichia coli | Aloisio 2014 [30]a | IAP n = 26 Control n = 26 |  | IAP: M 8.18 (R 4.09-12.70) Control: M 9.03 (R 5.61-11.78) NS |  |  |
Bacteroides fragilis | Aloisio 2014 [30]a | IAP n = 26 Control n = 26 |  | IAP: M 8.17 (R 4.68-11.99) Control: M 8.53 (R 5.22-11.16) NS |  |  |
Corvaglia 2016 [36]a | IAP n = 35 Control n = 29 |  | IAP: Md 7.71 (IQR 5.80-9.33) Control: Md 7.75 (IQR 5.87-9.61) p > 0.05 | IAP: Md 7.36 (IQR 5.80-9.09) Control: Md 8.51 (IQR 5.86-9.37) p > 0.05 |  | |
Clostridium difficile | Aloisio 2014 [30]a | IAP n = 26 Control n = 26 |  | IAP: M 3.89 (R 3.12-4.80) Control: M 3.70 (R 2.85-5.46) NS |  |  |
Total bacteria | Mazzola 2016 [57]a | Breast-fed IAP n = 7 Breast-fed Control n = 7 Mixed-fed IAP n = 6 Mixed-fed Control n = 6 |  | All groups: R 9.38-9.71 | All groups: R 9.53-9.83 |  |
Arboleya 2015 [32] | IAP n = 14 Control n = 13 |  |  | Higher log cells/g in IAP, p < 0.05 |  |