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Table 2 Overview of maternal characteristics, prevalence of analgesic use and associations between maternal characteristics and analgesic use

From: Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine

 

Study sample

Prevalence of analgesic use

Associations between possible predictors and analgesic use

n

n (% of n)

Crude OR (95% CI)

Adjusted OR (95% CI)

Maternal age at delivery

  < 25

165

77 (46.7)

1.00 (0.98–1.02)

0.99 (0.97–1.01)

 25–30

588

304 (51.7)

 31–35

768

385 (50.1)

  > 35

446

205 (46.0)

Parity

 First time mother

988

450 (45.6)

1

1

  ≥ 1 previous child

993

527 (53.1)

1.37 (1.13–1.65)

1.38(1.11–1.72)

Marital status

 Married/cohabiting

1910

947 (49.6)

1

1

 Single/divorced/separated

44

19 (43.2)

0.74 (0.40–1.39)

0.62 (0.32–1.21)

Education

 College/university

1294

609 (47.1)

1

1

 Primary/secondary school

606

332 (54.8)

1.27 (1.04–1.56)

1.07 (0.85–1.35)

Smoking at time of delivery

 No

1841

893 (48.5)

1

1

 Yes

76

52 (68.4)

2.25 (1.35–3.75)

1.89 (1.09–3.28)

Alcohol in pregnancy

 No

1866

918 (49.2)

1

1

 Yes

82

46 (56.1)

1.41 (0.87–2.28)

1.60 (0.95–2.69)

Symptoms of depression or anxiety in pregnancy

 No

1684

806 (47.9)

1

1

 Yes

291

170 (58.4)

1.41 (1.07–1.84)

0.86 (0.63–1.18)

Chronic diseases

 None

831

381 (45.8)

1

1

 1 disease

747

368 (49.3)

1.10 (0.89–1.35)

1.08 (0.86–1.35)

  ≥ 2 diseases

392

223 (56.9)

1.45 (1.12–1.88)

1.36 (1.03–1.79)

Pregnancy related diseases

 None

1777

878 (49.4)

1

1

  ≥ 1 disease

191

93 (48.7)

0.91 (0.66–1.24)

0.86 (0–62–1.21)

Somatic symptoms

 None

182

59 (32.4)

1.15 (1.10–1.20)

1.08 (1.03–1.14)

 1–2 symptoms

729

329 (45.1)

 3–4 symptoms

658

339 (51.5)

  ≥ 5 symptoms

412

250 (60.7)

Headache intensity

 Low

741

257 (34.7)

1.42 (1.33–1.50)

1.33 (1.25–1.43)

 Moderate

979

593 (60.6)

 High

183

120 (65.6)

Migraine pattern

 No history

1362

596 (43.8)

1

1

 Previous history

227

120 (52.9)

1.36 (1.01–1.83)

1.09 (0.80–1.49)

 Recent history prior to pregnancy

262

172 (65.6)

2.33 (1.74–3.13)

1.59 (1.16–2.18)

 Migraine in pregnancy

100

72 (72.0)

3.35 (2.07–5.41)

1.56 (0.93–2.63)

  1. Numbers do not add up to the total due to missing values (<5.0% for all variables). Complete cases n = 1721. Area under ROC curve = 0.69. Adj. ORs are adjusted for all covariates in the table. Significant associations are marked in bold. Maternal age, somatic symptoms and headache intensity were analyzed as continuous variables. Analgesics include paracetamol, NSAIDs, opioids and triptans, used for either headache or migraine