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Table 1 Comparison of sociodemographic, clinical-obstetric, laboratorial and therapeutic characteristics between iron-responsive and not iron-responsive pregnant women

From: Could the erythrocyte indices or serum ferritin predict the therapeutic response to a trial with oral iron during pregnancy? Results from the Accuracy study for Maternal Anaemia diagnosis (AMA)

 

Classification

P

Iron-responsive

Not iron-responsive

(n 37)

(n 102)a

Sociodemographic, clinical-obstetric, laboratorial characteristics at enrollment

Age (Mean ± SD)

26.3 ± 5.0

25.5 ± 4.7

0.387

Self-assigned ethnicity: n (%)

  

0.784

 Pardo (brown)

23 (62.2)

54 (52.9)

 

 Black

6 (16.2)

20 (19.6)

 White

6 (16.2)

19 (18.6)

 Others

2 (5.4)

9 (8.8)

BMI Atalah classification:b n (%)

  

0.094

 Underweight

6 (16.2)

21 (20.8)

 

 Health

24 (64.8)

47 (46.5)

 Overweight

2 (5.4)

22 (21.8)

 Obese

5 (13.5)

11 (10.9)

Educational level: n (%)

  

0.255

 Incomplete primary/middle school

1 (2.7)

4 (3.9)

 

 Complete primary/middle school

26 (70.3)

58 (56.9)

 Complete high school

10 (27.0)

32 (31.4)

 Complete graduation

0 (0.0)

8 (7.8)

Family income per capita (R$): Median (25th;75thcentiles)

333.33 (269.58;483.33)

350.00 (203.33;524.75)

0.987

Months since the last delivery: Median (25th;75thcentiles)

71.0 (44.3;90.6)

59.0 (44.8;85.0)

0.720

Nulliparous women: n (%)

21 (56.8)

58 (56.9)

0.991

Women using iron-supplement for ≥1 month: n (%)

3 (8.1)

20 (19.6)

0.083

Mean of Hb g/dL ± SD

10.1 ± 0.76

10.4 ± 0.58

0.018

Mean of Hb Z-scores ± SD

-1.8 ± 0.81

-1.4 ± 0.67

0.005

Serum ferritin (ng/mL): Median (25th;75thcentiles)

19.0 (9.0;33.0)

28.7 (11.1;53.0)

0.060

Characteristics of the therapeutic test with oral iron

Pregnancy weeks at start iron-therapy: Mean ± SD

21.6 ± 5.6

23.1 ± 4.6

0.121

Iron-therapy duration (days): Mean ± SD

52.6 ± 26.4

64.0 ± 26.1

0.025

Iron total doses: n (%)

  

0.046

1200–1760 mg

2 (5.4)

10 (9.8)

 

1800–2400 mg

16 (43.2)

22 (21.6)

>2400 mg

19 (51.4)

70 (68.6)

Gastrointestinal symptoms after starting oral iron: n (%)

29 (78.4)

63 (61.8)

0.054

  1. Hb haemoglobin concentration, R$ current Brazilian coin, SD standard deviation of 95 %, BMI body mass index
  2. aAmong the not iron-responsive women, one woman had no data on income and another did not have the BMI
  3. bAtalah et al 1997