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Table 5 Sensitivity Analysis: Crude and adjusted Odds Ratio of pregnancy hypertensive disorders and congenital malformations excluding AFR countries

From: Are hypertensive disorders in pregnancy associated with congenital malformations in offspring? Evidence from the WHO Multicountry cross sectional survey on maternal and newborn health

 

Chronic Hypertension

Pre-eclampsia

Eclampsia

Chronic HT/preeclampsia

 

Crude OR (CI 95 %)

Adj ORa (CI 95 %)

Crude OR (CI 95 %)

Adj ORa (CI 95 %)

Crude OR (CI 95 %)

Adj ORa (CI 95 %)

Crude OR (CI 95 %)

Adj ORa (CI 95 %)

Congenital malformation

        

Neural tube/Central Nervous System

4.4 (1.8–10.7)

2.4 (0.9–6.1)

1.3 (0.6–2.7)

1.0 (0.5–2.1)

-

-

9.7 (3.1–30.5)

4.2 (1.3–14.1)

Cardiac

2.6 (1.1–6.2)

1.9 (0.8–4.8)

3.1 (2.2–4.5)

2.4 (1.6–3.6)

1.2 (0.2–8.5)

-

3.7 (0.9–15.1)

2.3 (0.5–9.6)

Renal

7.4 (2.7–20.2)

3.7 (1.3–10.7)

2.5 (1.1–5.3)

1.7 (0.8–3.8)

-

-

20.5 (6.5–64.9)

8.4 (2.4–29.5)

Limb

5.1 (2.3–11.6)

4.0 (1.7–9.5)

1.6 (0.8–3.0)

1.3 (0.7–2.6)

-

-

9.4 (3.0–29.4)

7.1 (2.1–23.5)

Lip/Cleft/Palate

5.3 (1.9–14.2)

4.4 (1.6–12.0)

1.5 (0.6–3.3)

1.4 (0.6–3.3)

3.0 (0.4–21.7)

2.9 (0.4–20.4)

9.6 (2.4–38.8)

7.7 (1.8–31.9)

Chromosomal

3.0 (0.7–12.1)

0.9 (0.1–6.7)

1.4 (0.6–3.4)

0.8 (0.3–2.3)

-

-

5.5 (0.8–39.2)

0.7 (0.3–4.3)

  1. aOR Adjusted for Age, Education, Previous births and Marital Status with country and facility as random mixed effect variable