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Table 3 The difference in maternal characteristics between LGA and non-LGA pregnancies

From: Risk factors for large-for-gestational age infants in pregnant women with type 1 diabetes

Predictor

LGA

Non LGA

OR

CI

P value

(n = 117)

(n = 142)

Weight first visit (kg)

70.9 ± 10.6

69.0 ± 10.9

1.01

0.99–1.04

0.25

Weight at delivery (kg)

84.1 ± 11.1

80.4 ± 10.8

1.03

1.01–1.06

0.016

BMI before pregnancy (kg/m2)

25.2 ± 3.7

25.3 ± 3.8

0.99

0.92–1.06

0.80

Obesitya

11.1 % (n = 13)

10.7 % (n = 15)

1.01

0.44–2.32

0.99

Overweighta

32.5 % (n = 38)

35.0 % (n = 49)

1.29

0.76–2.18

0.35

Weight gain during pregnancy (kg)

13.2 ± 4.8

11.4 ± 5.2

1.08

1.02–1.13

0.008

Excessive weight gain

45.3 % (n = 53)

25.2 % (n = 38)

2.22

1.29–3.70

0.003

HbA1c before pregnancy mmol/mol (%)

53 ± 10

51 ± 11

1.28

0.95–1.72

0.10

(7.0 ± 0.9)

(6.8 ± 1.0)

HbA1c trimester 1 mmol/mol (%)

50 ± 10

48 ± 8

1.49

1.10–2.02

0.010

(6.7 ± 0.9)

(6.5 ± 0.8)

HbA1c trimester 2 mmol/mol (%)

42 ± 7

40 ± 8

1.61

0.98–2.65

0.06

(6.0 ± 0.6)

(5.8 ± 0.7)

HbA1c trimester 3 mmol/mol (%)

44 ± 6

42 ± 7

1.82

1.16–2.86

0.010

(6.2 ± 0.5)

(6.0 ± 0.6)

HbA1c < 42 mmol/mol (6 %) trimester 1

12.7 % (n = 14)

25.4 % (n = 35)

0.47

0.26–0.86

0.015

HbA1c < 42 mmol/mol (6 %) trimester 2

50.9 % (n = 56)

67.4 % (n = 93)

0.47

0.27–0.80

0.005

HbA1c < 42 mmol/mol (6 %) trimester 3

30.1 % (n = 31)

40.9 % (n = 52)

0.61

0.37–1.02

0.06

  1. LGA large-for-gestational-age infant, BMI Body Mass Index
  2. Results are given as mean (SD) or % (n); Bold indicates statistically significant associations, p < 0.05
  3. Odds ratio (95 %)
  4. areference category: normal weight with BMI < 25 kg/m2
  5. Logistic regression models were used to analyze the association between several clinical variables and LGA as binary outcome