Skip to main content

Table 6 Median hormone concentrations (10th-90th percentiles) and median change by trimester in 21 consecutive pregnancies a

From: Hormone concentrations throughout uncomplicated pregnancies: a longitudinal study

 

Pregnancy 1

Pregnancy 2

Median change

pWS b

Estradiol (ng/mL)

    

 1st trimester

2.32 (1.27–3.76)

1.98 (1.11–3.58)

−0.3 (−1.3; −1.3)

0.10

 2nd trimester

9.00 (5.91–13.3)

7.96 (5.21–13.2)

−0.3 (−0.9; 1.3)

0.18

 3rd trimester

22.6 (16.2–34.2)

20.0 (14.2–32.0)

−0.2 (−0.9; 0.5)

0.07

Estrone (ng/mL)

    

 1st trimester

0.73 (0.42–1.60)

0.73 (0.28–1.50)

−0.2 (−1.1; 0.5)

0.11

 2nd trimester

4.19 (2.03–6.76)

3.90 (1.67–8.17)

−0.2 (−1.0; 0.4)

0.10

 3rd trimester

8.00 (4.34–17.1)

7.80 (3.32–12.2)

−0.3 (−0.6; 0.2)

0.08

Progesterone (ng/mL)

    

 1st trimester

30.6 (22.1–47.4)

31.2 (22.9–45.0)

0 (−0.5; 0.6)

0.65

 2nd trimester

56.9 (39.3–85.3)

62.3 (40.4–78.7)

−0.1 (−0.8; 1.0)

0.96

 3rd trimester

161 (127–207)

165 (123–225)

0.1 (−0.7; 0.5)

0.55

Testosterone (ng/mL)

    

 1st trimester

0.84 (0.52–1.38)

0.78 (0.46–1.43)

0 (−1.2; 0.5)

0.31

 2nd trimester

1.10 (0.68–1.67)

1.02 (0.55–1.50)

−0.2 (−0.9; 0.6)

0.09

 3rd trimester

1.04 (0.60–2.88)

0.89 (0.60–1.45)

−0.4 (−1.0; 0.2)

0.002

  1. a Conversion from ng/ml to nmol/l (SI units): estradiol*3.671, estrone*3.699, progesterone*3.18, testosterone*3.467, and prolactin*0.04348
  2. b p-value obtained from the Wilcoxon signed rank sum test