From: Risk factors for ectopic pregnancy: a multi-center case-control study
 | EP | IUP | OR [95 % CI] | p value | ||
---|---|---|---|---|---|---|
n a | (%) | n a | (%) | |||
Reproductive history | ||||||
 Number of previous abortions | ||||||
  0 | 873 | (36.88) | 930 | (38.49) | Reference | 0.71 |
  1 | 763 | (32.23) | 756 | (31.29) | 1.08 [0.94, 1.23] | |
  2 | 485 | (20.49) | 497 | (20.57) | 1.04 [0.89, 1.21] | |
   ≥ 3 | 246 | (10.39) | 233 | (9.64) | 1.13 [0.92, 1.38] | |
 Parity | ||||||
  0 | 1143 | (48.29) | 1280 | (52.98) | Reference | <10−3 |
  1 | 994 | (41.99) | 973 | (40.27) | 1.14 [1.02, 1.30] | |
   ≥ 2 | 230 | (9.72) | 163 | (6.75) | 1.58 [1.27, 1.96] | |
Gynecologic history | ||||||
 Previous EP | ||||||
  No | 2093 | (86.81) | 2363 | (97.81) | Reference | <10−3 |
  Yes | 318 | (13.19) | 53 | (2.19) | 6.77 [5.04, 9.11] | |
 Serum Chlamydia trachomatis IgG test | ||||||
  Negative | 1648 | (69.13) | 2099 | (89.55) | Reference | <10−3 |
  Positive | 736 | (30.87) | 245 | (10.45) | 3.83 [3.27, 4.48] | |
 Previous infertility | ||||||
  No | 2005 | (83.26) | 2286 | (95.65) | Reference | <10−3 |
  Yes | 403 | (16.74) | 104 | (4.35) | 4.42 [3.53, 5.53] | |
 Categories of infertility | ||||||
  No | 2005 | (83.26) | 2286 | (95.65) | Reference | <10−3 |
  Tubal infertility | 326 | (13.54) | 73 | (3.05) | 5.09 [3.92, 6.61] | |
  Non-tubal infertility | 77 | (3.20) | 31 | (1.30) | 2.83 [1.86, 4.32] | |
   ARTs applied in the current cycle of conceptionb | ||||||
    Spontaneous pregnancy | 278 | (68.98) | 72 | (69.23) | Reference | <10−3 |
    IVF-ET | 58 | (14.39) | 3 | (2.88) | 5.01 [1.53, 16.44] | |
    Other ARTsc | 46 | (11.41) | 18 | (17.31) | 0.66 [0.36, 1.21] | |
    Chinese herb | 21 | (5.21) | 11 | (10.58) | 0.49 [0.23, 1.07] | |
Surgical history | ||||||
 Previous cesarean sectiond | ||||||
  No | 691 | (56.09) | 624 | (54.74) | Reference | 0.79 |
  Yes | 541 | (43.91) | 516 | (45.26) | 0.95 [0.81, 1.11] | |
 Previous adnexal surgery | ||||||
  No | 1985 | (82.33) | 2322 | (96.19) | Reference | <10−3 |
  Yes | 426 | (17.67) | 92 | (3.81) | 5.42 [4.29, 6.84] | |
   Specific adnexal surgerye | ||||||
    Ovarian surgery | 64 | (15.02) | 36 | (39.13) | 2.08 [1.38, 3.14] | <10−3 |
    Surgery for EP | 237 | (55.62) | 38 | (41.30) | 7.30 [5.15, 10.33] | |
    Tubal reconstructive surgery | 90 | (21.13) | 14 | (15.22) | 7.52 [4.27, 13.25] | |
    Female sterilization | 21 | (4.93) | 2 | (2.17) | 12.28 [2.88, 52.45] | |
    Reversal of tubal sterilization | 14 | (3.29) | 2 | (2.17) | 8.19 [1.86, 36.07] | |
  Previous appendectomy | ||||||
  No | 2303 | (95.84) | 2346 | (97.47) | Reference | 0.01 |
  Yes | 100 | (4.16) | 61 | (2.53) | 1.67 [1.21, 2.31] |