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Table 2 History of reproduction, gynecology, and surgery of all enrolled participates

From: Risk factors for ectopic pregnancy: a multi-center case-control study

 

EP

IUP

OR [95 % CI]

p value

n a

(%)

n a

(%)

Reproductive history

 Number of previous abortions

  0

873

(36.88)

930

(38.49)

Reference

0.71

  1

763

(32.23)

756

(31.29)

1.08 [0.94, 1.23]

  2

485

(20.49)

497

(20.57)

1.04 [0.89, 1.21]

   ≥ 3

246

(10.39)

233

(9.64)

1.13 [0.92, 1.38]

 Parity

  0

1143

(48.29)

1280

(52.98)

Reference

<10−3

  1

994

(41.99)

973

(40.27)

1.14 [1.02, 1.30]

   ≥ 2

230

(9.72)

163

(6.75)

1.58 [1.27, 1.96]

Gynecologic history

 Previous EP

  No

2093

(86.81)

2363

(97.81)

Reference

<10−3

  Yes

318

(13.19)

53

(2.19)

6.77 [5.04, 9.11]

 Serum Chlamydia trachomatis IgG test

  Negative

1648

(69.13)

2099

(89.55)

Reference

<10−3

  Positive

736

(30.87)

245

(10.45)

3.83 [3.27, 4.48]

 Previous infertility

  No

2005

(83.26)

2286

(95.65)

Reference

<10−3

  Yes

403

(16.74)

104

(4.35)

4.42 [3.53, 5.53]

 Categories of infertility

  No

2005

(83.26)

2286

(95.65)

Reference

<10−3

  Tubal infertility

326

(13.54)

73

(3.05)

5.09 [3.92, 6.61]

  Non-tubal infertility

77

(3.20)

31

(1.30)

2.83 [1.86, 4.32]

   ARTs applied in the current cycle of conceptionb

    Spontaneous pregnancy

278

(68.98)

72

(69.23)

Reference

<10−3

    IVF-ET

58

(14.39)

3

(2.88)

5.01 [1.53, 16.44]

    Other ARTsc

46

(11.41)

18

(17.31)

0.66 [0.36, 1.21]

    Chinese herb

21

(5.21)

11

(10.58)

0.49 [0.23, 1.07]

Surgical history

 Previous cesarean sectiond

  No

691

(56.09)

624

(54.74)

Reference

0.79

  Yes

541

(43.91)

516

(45.26)

0.95 [0.81, 1.11]

 Previous adnexal surgery

  No

1985

(82.33)

2322

(96.19)

Reference

<10−3

  Yes

426

(17.67)

92

(3.81)

5.42 [4.29, 6.84]

   Specific adnexal surgerye

    Ovarian surgery

64

(15.02)

36

(39.13)

2.08 [1.38, 3.14]

<10−3

    Surgery for EP

237

(55.62)

38

(41.30)

7.30 [5.15, 10.33]

    Tubal reconstructive surgery

90

(21.13)

14

(15.22)

7.52 [4.27, 13.25]

    Female sterilization

21

(4.93)

2

(2.17)

12.28 [2.88, 52.45]

    Reversal of tubal sterilization

14

(3.29)

2

(2.17)

8.19 [1.86, 36.07]

  Previous appendectomy

  No

2303

(95.84)

2346

(97.47)

Reference

0.01

  Yes

100

(4.16)

61

(2.53)

1.67 [1.21, 2.31]

  1. EP ectopic pregnancy, IUP intrauterine pregnancy, OR odds ratio, CI confidence interval, ART assisted reproduction technology, IVF-ET in vitro fertilization and embryo transfer
  2. aThe sum does not necessarily equal the sample size for all variables because of missing data
  3. bThe number of women with history of infertile was used as the denomintor to calculate the percentage
  4. cOther ARTs includes ovarian stimulation, intrauterine insemination, luteal phase support and combination of ovarian stimulation and luteal phase support
  5. dThe number of women having delivered a child was used as the denomintor to calculate the percentage
  6. eThe number of women experienced adnexal surgeries was used as the denomintor to calculate the percentage