The association between interpregnancy interval and birth weight: what is the role of maternal polyunsaturated fatty acid status?

Table 4 Results of the logistic regression analysis of the association between interpregnancy interval and unfavorable maternal essential fatty acid status

Interpregnancy interval (mo)		EPA¹			DHA¹			DGLA¹			AA¹
	N	% women in 1st Quintile	Mean ± SD concentration	Odds ratio²(95% CI)	% women in 1st Quintile	Mean ± SD concentration	Odds ratio²(95% CI)	% women in 1st Quintile	Mean ± (SD) concentration	Odds ratio²(95% CI)	% women in 5^thQuintile	Mean (±SD) concentration	Odds ratio²(95% CI)
< 6	60	23.3	0.66 ± 0.47	1.58 (0.79-3.17)	18.3	4.77 ± 1.20	1.60 (0.51-2.22)	25.0	3.30 ± 0.69	1.22 (0.62-2.37)	25.0	9.34 ± 1.71	1.09 (0.52-2.29)
6-11	276	11.2	0.68 ± 0.44	0.66 (0.39-1.10)	18.3	4.70 ± 1.08	1.12 (0.71-1.77)	22.8	3.41 ± 0.75	1.08 (0.71-1.65)	21.7	9.28 ± 1.56	0.97 (0.52-2.29)
12-17	280	11.8	0.67 ± 0.38	0.69 (0.42-1.16)	19.2	4.85 ± 1.08	0.81 (0.50-1.31	17.9	3.54 ± 0.74	0.79 (0.51-1.23)	21.1	9.28 ± 1.47	0.79 (0.49-1.28)
18-23	223	16.1	0.70 ± 0.53	1 (ref)	14.6	4.75 ± 1.13	1 (ref)	21.5	3.40 ± 0.70	1 (ref)	22.9	9.35 ± 1.72	1 (ref)
≥ 24	820	26.6	0.58 ± 0.45	1.88 (1.28-2.78)	17.3	4.57 ± 1.14	1.40 (0.96-2.06)	18.9	3.46 ± 0.77	0.85 (0.59-1.22)	17.9	9.66 ± 1.76	1.53 (1.04-2.25)
Total	1659		0.63 ± 0.45			4.67 ± 1.12			3.45 ± 0.75			9.48 ± 1.68

¹ EPA, eicosapentaenoic acid (20:5 n-3); DHA, docosahexaenoic acid (22:6 n-3), DGLA; dihomo-γ-linolenic acid (20:3 n-6), AA; arachidonic acid (20:4 n-6).
² Odds ratios resulting from logistic regression analysis of the association of interpregnancy interval with having an unfavorable blood concentration of either of four essential fatty acids. For each fatty acid, the quintile having strongest association with adverse pregnancy outcome (see Table 3) was designated as the unfavorable fatty acid outcome. (EPA: Quintile 1, DHA: Quintile 1, DGLA: Quintile 1, AA: Quintile 5).

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