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Table 5 Fetal, neonatal and perinatal mortality rates of suggested perinatal period by single and double embryo transfers

From: Perinatal mortality following assisted reproductive technology treatment in Australia and New Zealand, a public health approach for international reporting of perinatal mortality

Number of embryos transferred and plurality

Number

Mortality rate and (95% CI) /denominator

 

Total births

Fetal deaths

Neonatal deaths

Fetal 1000 births

Neonatal /live births

Perinatal /1000 births

From ≥ 20 weeks gestational age to < 7 survival days after birth

Single embryo transfer

Singletons

24199

235

38

9.7(8.5-11.0)

1.6(1.1-2.1)

11.3(9.9-12.6)

Twins

990

41

9

41.4(28.7-54.1)

9.5(3.3-15.7)

50.5(36.5-64.5)

All births1

25220

277

47

11.0(9.7-12.3)

1.9(1.3-2.4)

12.8(11.4-14.2)

Double embryo transfer

Singletons

15115

172

29

11.4(9.7-13.1)

1.9(1.2-2.6)

13.3(11.5-15.1)

Twins

9150

151

68

16.5(13.9-19.1)

7.6(5.8-9.4)

23.9(20.8-27.1)

All births1

24525

343

106

14.0(12.5-15.5)

4.4(3.5-5.2)

18.3(16.6-20.0)

All transfers 2

Singletons

39624

410

69

10.3(9.3-11.3)

1.8(1.3-2.2)

12.1(11.0-13.2)

Twins

10292

193

77

18.8(16.1-21.4)

7.6(5.9-9.3)

26.2(23.1-29.4)

All births1

50252

625

157

12.4(11.5-13.4)

3.2(2.7-3.7)

15.6(14.5-16.7)

From ≥ 22 weeks gestational age to < 7 survival days after birth

Single embryo transfer

Singletons

24200

159

28

6.6(5.5-7.6)

1.2(0.7-1.6)

7.7(6.6-8.8)

Twins

990

28

6

28.3(17.8-38.8)

6.2(1.2-11.2)

34.3(22.8-45.9)

All births1

25108

187

34

7.4(6.4-8.5)

1.4(0.9-1.8)

8.8(7.6-10.0)

Double embryo transfer

Singletons

15046

118

17

7.8(6.4-9.3)

1.1(0.6-1.7)

9.0(7.5-10.5)

Twins

9075

95

50

10.5(8.4-12.6)

5.6(4.0-7.1)

16.0(13.4-18.6)

All births1

24353

225

72

9.2(8.0-10.4)

3.0(2.3-3.7)

12.2(10.8-13.6)

All transfers 2

Singletons

39461

279

47

7.1(6.2-7.9)

1.2(0.9-1.5)

8.3(7.4-9.2)

Twins

10199

124

56

12.2(10.0-14.3)

5.6(4.1-7.0)

17.6(15.1-20.2)

All births1

49981

416

110

8.3(7.5-9.1)

2.2(1.8-2.6)

10.5(9.6-11.4)

  1. 1include higher order multiples.
  2. 2include transfers of three or more embryos.