Hyperemesis gravidarum and pregnancy outcomes in the Norwegian mother and child cohort – a cohort study

Table 2 Differences in birthweight and gestational age for offspring of mothers with and without hyperemesis gravidarum (N = 71,468)

	N = 71,468	Mean	Crude estimate	Adjusted estimate	Adjusted estimate	Adjusted estimate
	N = 71,468	Mean	β [95% CI]	β [95% CI]^*	β [95% CI]^***	β [95% CI]^****
Birthweight
No hyperemesis (HG)	70,654	3602 gram	1 Reference	1 Reference	1 Reference	1 Reference
HG	814	3567 gram	−34.46 (−72.84 - 3.93 )	−46.89 (−80.53 -13.26)^**	−47.57 (−79.92- -13.21)^**	−23.42 (−56.71- 9.86 )^**
Gestational age
No HG	70,654	279.7 days	1 Reference	1 Reference	1 Reference	1 Reference
HG	814	278.0 days	−1.68 (−2.53- -0.84 )	−1.50 (−2.34- -0.67 )	-1.38 (−2.21- -0.55)	-0.97 (−1.80- -0.15 )

^*Adjusted for maternal age, parity, BMI, education and smoking habits.
^**Additional adjustment for gestational age and induction.
^***Additional adjustment for asthma, diabetes 1, thyroid disease, depression, anxiety, other psychological problems, anorexia, anaemia and vitamin B12 deficiency.
^****Adjustment for maternal weight gain.

ISSN: 1471-2393