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Table 4 Comparison of all collected data between deceased and surviving septic neonates (univariate analysis)

From: Risk factors and prognosis for neonatal sepsis in southeastern Mexico: analysis of a four-year historic cohort follow-up

Variable

Deceased

Surviving

P

 

N = 49 (%)

N = 465 (%)

 

Neonate-related

Gender (feminine/masculine)

21/28

212/253

0.41

Gestational age (wk)*

31.3 ± 5.2

34.0 ± 4.1

<0.0001

Birth weight (g)*

1486 ± 867

2130 ± 852

<0.0001

Height (cm)*

38.2 ± 6.2

44.0 ± 5.6

<0.0001

Premature (≤37 wks)

38 (77.5)

153 (32.2)

0.08

Postmature (≥42 wks)

1 (2.0)

4 (0.9)

0.39

Product of multiple pregnancy

7 (14.3)

34 (7.3)

0.08

Abnormal umbilical cord

14 (28.6)

117 (25.2)

0.35

With perinatal asphyxia

9 (18.4)

8 (1.7)

<0.0001

With intrauterine hypoxia

3 (6.1)

7 (1.5)

0.06

Apgar score ≤5

42 (85.7)

232 (49.9)

<0.0001

With fetal distress

13 (26.5)

73 (15.7)

0.04

Maternal-related

Age (yrs)*

27.0 ± 5.8

26.3 ± 5.5

0.42

Low educative level

26 (53.1)

258 (55.5)

0.43

Gestations*

2.3 ± 1.3

1.9 ± 1.2

0.06

Abortions*

0.4 ± 0.7

0.2 ± 0.5

0.01

Non-adequate pregnancy control

30 (61.2)

228 (49.0)

0.07

With threat of abortion during this pregnancy

19 (38.8)

120 (25.8)

0.04

Abnormal placenta

15 (30.6)

71 (15.3)

0.008

Abnormal amniotic fluid

20 (40.8)

139 (29.9)

0.08

Dystocic delivery

16 (32.7)

135 (29.0)

0.35

Cesarean section

32 (65.3)

327 (70.3)

0.28

Premature membrane rupture >12 h

10 (20.4)

158 (34.0)

0.03

Premature membrane rupture >48 h

7 (14.3)

130 (28.0)

0.02

Premature membrane rupture >24 h

5 (10.2)

80 (17.2)

0.14

Amnionitis

0

4 (0.9)

0.66

Preeclampsia ≤35 gestational wks

3 (6.1)

25 (5.4)

0.51

Preeclampsia >35 gestational wks

2 (4.1)

24 (5.2)

0.54

Metabolic disease ≤35 gestational wks

4 (8.2)

23 (4.9)

0.25

Metabolic disease >35 gestational wks

1 (2.0)

25 (5.4)

0.26

Infectious disease ≤35 gestational wks

17 (34.7)

147 (31.6)

0.38

Infectious disease >35 gestational wks

7 (14.3)

72 (15.5)

0.51

Clinical course- and medical care-related

Reanimation required

45 (91.8)

294 (63.2)

<0.0001

Mechanical ventilation required

37 (75.5)

123 (26.5)

<0.0001

O2 inspiration fraction >60% required

23 (46.9)

72 (15.5)

<0.0001

Continuous positive airway pressure required

6 (12.2)

18 (3.9)

0.02

Surfactant administration

16 (32.7)

33 (7.1)

<0.0001

Respiratory complication

1 (2.0)

34 (7.3)

0.13

Intraventricular bleeding

9 (18.4)

11 (2.4)

<0.0001

Surgical procedure required

4 (8.2)

19 (2.2)

0.03

Invasive medical procedure required

48 (97.8)

245 (52.5)

<0.0001

  1. *Mean ± Standard deviation (SD).